Drug resistance in amoebiasis.

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dc.contributor.authorBansal, Devendraen_US
dc.contributor.authorMalla, Nancyen_US
dc.contributor.authorMahajan, R Cen_US
dc.date.accessioned2006-02-01en_US
dc.date.accessioned2009-05-27T06:56:42Z
dc.date.available2006-02-01en_US
dc.date.available2009-05-27T06:56:42Z
dc.date.issued2006-02-01en_US
dc.description39 references.en_US
dc.description.abstractAmoebiasis caused by Entamoeba histolytica, is a major public health problem in developing countries. Morphologically similar E. dispar is non pathogenic. Because of the redefinition of E. histolytica and E. dispar, and the limited number of antiamoebic drugs available, a new approach to treat such individuals is necessary. The cost of treating asymptomatic individuals is highly exorbitant and not justifiable. The indiscriminate use of antiamoebic drugs can result in increased minimum inhibitory concentration (MIC) values against Entamoeba species, and treatment failure may emerge as an important public health problem. Development of new antiamoebic drugs is still in infancy and vaccine development appears to be distant dream. In future, the development of drug resistance may seriously affect the control of disease. This review discusses the factors involved in drug resistance mechanisms developed by the parasite.en_US
dc.description.affiliationDepartment of Parasitology, Post Graduate Institute of Medical Education & Research, Chandigarh, India.en_US
dc.identifier.citationBansal D, Malla N, Mahajan RC. Drug resistance in amoebiasis. Indian Journal of Medical Research. 2006 Feb; 123(2): 115-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/18620
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntiprotozoal Agents --pharmacologyen_US
dc.subject.meshDrug Resistance, Multipleen_US
dc.subject.meshEntamoeba histolytica --drug effectsen_US
dc.subject.meshEntamoebiasis --drug therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshMetronidazole --pharmacologyen_US
dc.titleDrug resistance in amoebiasis.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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