Reviewing host proteins of Rhabdoviridae: Possible leads for lesser studied viruses.
Loading...
Date
2011-12
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Rhabdoviridae, characterized by bullet-shaped viruses, is known for its diverse host range, which includes
plants, arthropods, fishes and humans. Understanding the viral–host interactions of this family can prove
beneficial in developing effective therapeutic strategies. The host proteins interacting with animal rhabdoviruses
have been reviewed in this report. Several important host proteins commonly interacting with animal
rhabdoviruses are being reported, some of which, interestingly, have molecular features, which can serve as
potential antiviral targets. This review not only provides the generalized importance of the functions of animal
rhabdovirus-associated host proteins for the first time but also compares them among the two most studied
viruses, i.e. Rabies virus (RV) and Vesicular Stomatitis virus (VSV). The comparative data can be used for
studying emerging viruses such as Chandipura virus (CHPV) and the lesser studied viruses such as Piry virus
(PIRYV) and Isfahan virus (ISFV) of the Rhabdoviridae family.
Description
Keywords
host proteins, protein interactions, Rabies virus, Rhabdovirus, Vesicular Stomatitis virus
Citation
Guleria A, M Kiranmayi, Sreejith R, Kumar K, Sharma SK, Gupta S. Reviewing host proteins of Rhabdoviridae: Possible leads for lesser studied viruses. Journal of Biosciences. 2011 Dec; 36 (5): 929-937.