Clinical utility of TIRADS and ultrasound elastography in characterization of thyroid nodules

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dc.contributor.authorSachdev, Namritaen_US
dc.contributor.authorSanaen_US
dc.contributor.authorGupta, Shivanien_US
dc.contributor.authorPrasad, Akhilaen_US
dc.date.accessioned2020-11-18T09:57:33Z
dc.date.available2020-11-18T09:57:33Z
dc.date.issued2019-02
dc.description.abstractBackground: Thyroid nodules are a common entity in an iodine deficient population, however malignant nodules are relatively uncommon with excellent prognosis. Ultrasound elastography is a useful tool for characterization of nodules and allows selection of tumors for FNAC. This study aimed to evaluate the diagnostic value of strain elastography and acoustic radiation force impulse (ARFI) imaging in differentiating malignant from benign thyroid nodules.Methods: This study included 100 thyroid nodules evaluated using ultrasound TIRADS classification. Strain elastography evaluated the nodules using the elasticity score and strain ratio followed by VTI and shear wave velocity generated from ARFI data to characterize the nodules. Final diagnoses were obtained from cytological and/or histological evaluation. The diagnostic performance of the two elastography methods was analyzed and compared by multiple receiver operating characteristic curve analysis.Results: Of the 100 thyroid nodules observed in 100 patients (82 females and 18 males), 22% were malignant nodules and 78% were benign. The cut off values for elasticity scores, mean SR, VTI grade and mean SWV for predicting malignant thyroid nodules were greater than or equal to score 2, 2.4, grade 3, 2.5m/s respectively. The area under the receiver operating characteristic curve for elasticity score, mean SR, VTI grade and mean SWV was 0.79, 0.78, 0.89 and 0.84, respectively (P>0.05) and the accuracy was 74, 81.6, 88 and 87.5%, respectively (P>0.05). The accuracy of the combined use of conventional sonography, strain elastography and ARFI imaging was 85.6% respectively, which was higher than that of conventional sonography (P>0.05).Conclusions: Strain elastography and ARFI imaging have high sensitivity and specificity for differentiating malignant from benign thyroid nodules and therefore have good clinical utility in evaluating these lesions.en_US
dc.identifier.affiliationsDepartment of Radiodiagnosis, PGIMER and Dr. RML Hospital, New Delhi, Indiaen_US
dc.identifier.citationSachdev Namrita, Sana, Gupta Shivani, Prasad Akhila. Clinical utility of TIRADS and ultrasound elastography in characterization of thyroid nodules. International Journal of Research in Medical Sciences. 2019 Feb; 7(2): 328-333en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/211121
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber2en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20190329en_US
dc.subjectAcoustic radiation force impulseen_US
dc.subjectShear wave velocityen_US
dc.subjectStrain elastographyen_US
dc.subjectStrain ratioen_US
dc.subjectThyroid noduleen_US
dc.subjectVirtual touch tissue imagingen_US
dc.titleClinical utility of TIRADS and ultrasound elastography in characterization of thyroid nodulesen_US
dc.typeJournal Articleen_US
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