Hepatitis in patients with surgical complications of pulmonary tuberculosis.

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dc.contributor.authorAnsari, M Men_US
dc.contributor.authorBeg, M Hen_US
dc.contributor.authorHaleem, Sen_US
dc.date.accessioned1991-07-01en_US
dc.date.accessioned2009-05-27T10:15:46Z
dc.date.available1991-07-01en_US
dc.date.available2009-05-27T10:15:46Z
dc.date.issued1991-07-01en_US
dc.description.abstractDuring last six years, 2250 patients were treated in Cardiothoracic Unit for thoracic complications of pulmonary tuberculosis. During isoniazid/streptomycin/ethambutol treatment, 2 patients out of 710 (0.28%) developed hepatitis. During isoniazid/rifampicin/ethambutol therapy, 18 patients out of 1540 (1.17%) suffered from jaundice; all these patients were above 30 years of age, and many had gross anemia (Hb less than 9 gm%), hypoalbuminemia (less than 3 gm%) and radiologically far-advanced disease in comparison to those who did not develop jaundice (p less than 0.05). Jaundice subsided completely after discontinuation of isoniazid and/or rifampicin which were re-instituted successfully after recovery without recurrence of hepatitis. It is suggested that the development of hepatitis does not warrant total withdrawal of these two highly effective bactericidal drugs but they should be tried again cautiously after recovery from jaundice.en_US
dc.description.affiliationDepartment of Cardiothoracic Surgery, J.N. Medical College, Aligarh Muslim University.en_US
dc.identifier.citationAnsari MM, Beg MH, Haleem S. Hepatitis in patients with surgical complications of pulmonary tuberculosis. The Indian Journal of Chest Diseases & Allied Sciences. 1991 Jul-Sep; 33(3): 133-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/29527
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/iae/iaem.shtmlen_US
dc.subject.meshAdulten_US
dc.subject.meshAntitubercular Agents --adverse effectsen_US
dc.subject.meshDrug Therapy, Combinationen_US
dc.subject.meshEthambutol --administration & dosageen_US
dc.subject.meshFemaleen_US
dc.subject.meshHepatitis, Toxic --epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIsoniazid --administration & dosageen_US
dc.subject.meshMaleen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRifampin --administration & dosageen_US
dc.subject.meshStreptomycin --administration & dosageen_US
dc.subject.meshTuberculosis, Pulmonary --complicationsen_US
dc.titleHepatitis in patients with surgical complications of pulmonary tuberculosis.en_US
dc.typeJournal Articleen_US
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