Scavenging potential of reactive oxygen species by Tetra-hydrocurcumin.

Simple item page
dc.contributor.authorPrabhu, P Radhika
dc.contributor.authorHegde, Karunakar
dc.contributor.authorShabaraya, A R
dc.contributor.authorRao, M N A
dc.date.accessioned2014-05-13T10:51:27Z
dc.date.available2014-05-13T10:51:27Z
dc.date.issued2011-07
dc.description.abstractIn this study, the scavenging response of tetrahydrocurcumin (THC) was evaluated by using series of in vitro models of chemicals compared with standard antioxidant Trolox and curcumin. The THC exhibited its radical scavenging effect in concentration dependent manner on super oxide, hydroxyl radicals, ferric ions, 1,1-diphenyl, 2-picryl hydrazyl (DPPH) and 2,2- azinobis-(3-ethylbenzothiazoline-6-sulphonate) (ABTS). The THC was also evaluated for its inhibitory response on membrane lipid peroxidation by thiobarbituric acid reactive substances (TBARS) using rat liver homogenate. The present study shows that THC is a good antioxidant compared to the standard antioxidant, Trolox. Although, THC is less active than curcumin in many models, the increased superoxide scavenging and decreased ability to reduce ferric ions offers interesting advantages over curcumin. The THC was also effective in preventing membrane lipid peroxidation induced by FeSO4/ascorbate in concentration dependent manner.en_US
dc.identifier.citationPrabhu P Radhika, Hegde Karunakar, Shabaraya A R, Rao M N A. Scavenging potential of reactive oxygen species by Tetra-hydrocurcumin. Journal of Applied Pharmaceutical Science. 2011 July; 1(5): 114-118.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/150822
dc.language.isoenen_US
dc.source.urihttps://www.japsonline.com/counter.php?aid=96en_US
dc.subjectAntioxidanten_US
dc.subjectFree radicalsen_US
dc.subjectLipid peroxidationen_US
dc.subjectTetrahydrocurcuminen_US
dc.titleScavenging potential of reactive oxygen species by Tetra-hydrocurcumin.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
japs2011v1n5p114.pdf
Size:
408.95 KB
Format:
Adobe Portable Document Format
Description:
Research article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Journal of Applied Pharmaceutical Science (JAPS)