Intrapulmonary arteriovenous shunt in children with chronic liver disease: clinical features, laboratory data and outcome.

dc.contributor.authorMahmoodi, Eftekharen_US
dc.contributor.authorKianifar, Hamid Rezaen_US
dc.contributor.authorPartovi, Siminen_US
dc.contributor.authorMafinejad, Shahinen_US
dc.contributor.authorBozorgnia, Abolghasemen_US
dc.date.accessioned2008-01-11en_US
dc.date.accessioned2009-05-29T02:59:09Z
dc.date.available2008-01-11en_US
dc.date.available2009-05-29T02:59:09Z
dc.date.issued2008-01-11en_US
dc.description.abstractOBJECTIVE: To determine the frequency of hepatopulmonary syndrome in children with chronic liver disease, and its clinical and biochemical associations. METHOD: This study included 53 children with chronic liver disease, who underwent contrast echocardiography with agitated saline and measurement of arterial blood gases. RESULTS: Of the 53 patients studied, 18 had intrapulmonary shunting of blood. This shunting was associated with presence of palpable spleen, cyanosis and dyspnea, but not with abnormalities in the biochemical tests of liver function. At 1-year follow-up, there were 5 deaths among 18 patients with intrapulmonary shunt. In a logistic regression model, PaO 2 < 70 mmHg was found to be a predictor of death (p< 0.05). CONCLUSION: Intrapulmonary shunting is a common and important complication in children with chronic liver disease.en_US
dc.description.affiliationDepartment of Pediatric Cardiology, Ghaem Medical Center, Mashhad University of Medical Sciences, Mashhad, Iran.en_US
dc.identifier.citationMahmoodi E, Kianifar HR, Partovi S, Mafinejad S, Bozorgnia A. Intrapulmonary arteriovenous shunt in children with chronic liver disease: clinical features, laboratory data and outcome. Indian Journal of Gastroenterology. 2008 Jan-Feb; 27(1): 16-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/64797
dc.language.isoengen_US
dc.source.urihttps://www.indianjgastro.comen_US
dc.subject.meshAdolescenten_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshChronic Diseaseen_US
dc.subject.meshFemaleen_US
dc.subject.meshHepatopulmonary Syndrome --etiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshLiver Diseases --complicationsen_US
dc.subject.meshMaleen_US
dc.titleIntrapulmonary arteriovenous shunt in children with chronic liver disease: clinical features, laboratory data and outcome.en_US
dc.typeJournal Articleen_US
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