Pathobiological Characteristics of Intestinal and Diffuse-Type of Gastric Carcinoma-Retrospective Study of Gastric Cancers

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dc.contributor.authorPriyadharshini, Men_US
dc.contributor.authorNarmadha, Ren_US
dc.contributor.authorDhanalakshmi, Sen_US
dc.contributor.authorNatarajan, Ren_US
dc.contributor.authorSubitha, S,en_US
dc.contributor.authorSuganthi, Cen_US
dc.contributor.authorPadmavathyen_US
dc.date.accessioned2019-11-04T04:57:57Z
dc.date.available2019-11-04T04:57:57Z
dc.date.issued2017-02
dc.description.abstractBackground: Gastric carcinomas have various pathological features. Based on patterns of growth and invasiveness, however, they fall into two types: diffuse type and intestinal type. These two types of carcinoma appear to be different in their histogenetic origins. Objectives: To analyse various types of gastric cancer reported in last five years. To compare the features of intestinal and diffuse type gastric carcinoma including gross appearance, staging, grading of tumor. Materials and Methods: This was a retrospective study of 324 gastric cancer which were surgically resected and received over 5 years. The tumors were divided into groups according to their gross and microscopic patterns. Gross appearance was classified based on Borrmann classification. Microscopic features evaluated include tumor cell type, extent of invasion, degree of maturation, formation of glandular structures, nodal metastasis. Results: Totally 320 cases of gastric cancer were received of which 218(68%) were male, 102(32%) were female. Gastric cancers are rare below the age of 30 years. Comparing the type of gastric cancer intestinal type were 269(84%), diffuse type were 24(7.5%) and other type of gastric cancer including GIST, lymphoma, mucinous adenocarcinoma were 27(8.5%). Younger patients have higher stage of lymph node metastasis in diffuse type, but not for the intestinal type. Conclusion: Gastric cancer more common in male (M:F= 2:1) and most frequently seen in 5th decade. Intestinal type constitutes the most common type of gastric tumor. Gross appearance of diffuse type was predominantly infiltrative (79%).en_US
dc.identifier.affiliationsAssistant Professor, Madras Medical College, Institute of Pathology, Tamil Nadu, India, narmi_ram@yahoo.co.inen_US
dc.identifier.affiliationsAssistant Professor, Madras Medical College, Institute of Pathology, Tamil Nadu, India, dhanadinesh25@gmail.comen_US
dc.identifier.affiliationsAssistant Professor, Madras Medical College, Institute of Pathology, Tamil Nadu, India, aprn75@gmail.comen_US
dc.identifier.affiliationsAssistant Professor, Madras Medical College, Institute of Pathology, Tamil Nadu, India, subithatsk@gmail.comen_US
dc.identifier.affiliationsProfessor, Madras Medical College, Institute of Pathology, Tamil Nadu, Indiaen_US
dc.identifier.affiliationsAssistant Professor, Madras Medical College, Institute of Pathology, Tamil Nadu, India, padmavathi.rajagopalan29@gmail.comen_US
dc.identifier.citationPriyadharshini M, Narmadha R, Dhanalakshmi S, Natarajan R, Subitha S, Suganthi C, Padmavathy. Pathobiological Characteristics of Intestinal and Diffuse-Type of Gastric Carcinoma-Retrospective Study of Gastric Cancers. International Journal of Medical and Dental Sciences. 2017 Jul; 6(2): 1462-1467en_US
dc.identifier.issn2454-8952
dc.identifier.issn2320-1118
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/183612
dc.languageenen_US
dc.publisherDr. J.S. Sodhi Memorial Educational Societyen_US
dc.relation.issuenumber2en_US
dc.relation.volume6en_US
dc.source.urihttps://doi.org/10.18311/ijmds/2017/18833en_US
dc.subjectGastric Canceren_US
dc.subjectDiffuse Typeen_US
dc.subjectIntestinal Typeen_US
dc.subjectGross Appearanceen_US
dc.subjectGradingen_US
dc.subjectNodal Metastasisen_US
dc.subjectDentistryen_US
dc.titlePathobiological Characteristics of Intestinal and Diffuse-Type of Gastric Carcinoma-Retrospective Study of Gastric Cancersen_US
dc.typeJournal Articleen_US
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