Predictive value of electroencephalography and computed tomography in childhood non-traumatic coma.

Simple item page
dc.contributor.authorSinghi, Pratibha Den_US
dc.contributor.authorBansal, Arunen_US
dc.contributor.authorRamesh, Sen_US
dc.contributor.authorKhandelwal, Nen_US
dc.contributor.authorSinghi, Sunit Cen_US
dc.date.accessioned2005-06-30en_US
dc.date.accessioned2009-05-30T14:56:11Z
dc.date.available2005-06-30en_US
dc.date.available2009-05-30T14:56:11Z
dc.date.issued2005-06-30en_US
dc.description.abstractOBJECTIVES: To study value of electroencephalogram (EEG) and computed tomography (CT Scan) in predicting outcome of non-traumatic coma in children. METHODS: 100 consecutive children, between 2 months to 12 years, with non-traumatic coma, (Glasgow Coma Scale score < 8). Demographic and clinical data was recorded at admission. EEG and CT scan were done within 24 hours of admission. Etiologic diagnosis was assigned on basis of clinical data and relevant laboratory investigations. The outcome was recorded as survived and died. Among survivors it was graded as no disability, or mild, moderate, or severe disability. Odds ratio and/or relative risk (RR) with 95% confidence interval (C I) were calculated. RESULTS: EEG could be done in 60 patients (43 survived; 7 were normal, 8 had mild, 17 moderate and 11 severe disability) CT scan in 93 patients (60 survived; 11 were normal, 14 had mild, 21 moderate and 14 severe disability). A normal/borderline EEG was associated with good outcome (P = 0.001); 11 of 12 survived and of survivors 55% had no or mild disability. Electrocerebral silence on EEG was a predictor of death (OR = 44 -sub .95% Cl - 1.5-7372; P = 0.01). An abnormal EEG was associated with significant increase in risk of disability among survivors (RR = 2.6, 95% Cl = 1.2-5.4, P = 0.03). Among CT abnormalities intracranial bleed suggested increased risk of death (RR = 2.1; 95% Cl - 0.8-5.3; P = 0.058), while, hydrocephalus was associated with better survival (RR = 0.7; 95% CI - 0.5 to 0.96; P = 0.029). However, hydrocephalus when compared with other abnormal CT scan findings, was associated with higher risk of moderate and severe disability among survivors (P = 0.046) CONCLUSION: A normal CT scan and EEG, and some of the specific findings could be helpful in predicting outcome in children with non-traumatic coma. EEG and CT scan should be done at admission in all patients with non-traumatic coma if feasible.en_US
dc.description.affiliationDepartment of Pediatrics, Advanced Pediatrics Center, Post Graduate Institute of Medical Education and Research Center, Chandigarh, India. drsinghi@glide.net.inen_US
dc.identifier.citationSinghi PD, Bansal A, Ramesh S, Khandelwal N, Singhi SC. Predictive value of electroencephalography and computed tomography in childhood non-traumatic coma. Indian Journal of Pediatrics. 2005 Jun; 72(6): 475-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/83135
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshComa --diagnosisen_US
dc.subject.meshElectroencephalographyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshPredictive Value of Testsen_US
dc.subject.meshPrognosisen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshTomography, X-Ray Computeden_US
dc.titlePredictive value of electroencephalography and computed tomography in childhood non-traumatic coma.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Pediatrics