Comparison of effects of pyronaridine, amodiaquine, mefloquine and qinghaosu on rodent malaria.

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dc.contributor.authorShao, B Ren_US
dc.contributor.authorYe, X Yen_US
dc.contributor.authorChu, Y Hen_US
dc.date.accessioned2009-05-27T16:57:28Z
dc.date.available2009-05-27T16:57:28Z
dc.date.issued1992-03-01en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractBlood schizontocidal effect of antimalarials were compared by 4-day suppressive test with an extended observation period of 31 days. On a drug-sensitive Plasmodium berghei ANKA strain, pyronaridine (PND) exhibited the best effect, followed by amodiaquine (ADQ), mefloquine (MFQ), and qinghaosu (QHS). On a moderately chloroquine-resistant P. berghei NS line, the order of effects was the same, PND greater than ADQ greater than MFQ greater than QHS. On a highly pyronaridine-resistant P. berghei RP line, ADQ, MFQ and QHS showed cross resistance with PND.en_US
dc.description.affiliationInstitute of Parasitic Disease, Chinese Academy of Preventive Medicine, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai.en_US
dc.identifier.citationShao BR, Ye XY, Chu YH. Comparison of effects of pyronaridine, amodiaquine, mefloquine and qinghaosu on rodent malaria. The Southeast Asian Journal of Tropical Medicine and Public Health. 1992 Mar; 23(1): 59-63en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/36394
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/publication.htmen_US
dc.subject.meshAmodiaquine --administration & dosageen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntimalarials --administration & dosageen_US
dc.subject.meshArtemisininsen_US
dc.subject.meshDrug Administration Scheduleen_US
dc.subject.meshDrug Evaluation, Preclinicalen_US
dc.subject.meshDrug Resistanceen_US
dc.subject.meshFemaleen_US
dc.subject.meshMalaria --drug therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMefloquine --administration & dosageen_US
dc.subject.meshMiceen_US
dc.subject.meshNaphthyridines --administration & dosageen_US
dc.subject.meshPlasmodium bergheien_US
dc.subject.meshSesquiterpenes --administration & dosageen_US
dc.titleComparison of effects of pyronaridine, amodiaquine, mefloquine and qinghaosu on rodent malaria.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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