Maternal serum βhCG level and uterine artery doppler studies as predictors of pregnancy induced hypertension and intra uterine growth restriction: a prospective study

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dc.contributor.authorSheth, Vishal S.en_US
dc.contributor.authorNakum, Kanaklata D.en_US
dc.contributor.authorPatel, Mehul D.en_US
dc.contributor.authorLunagariya, Mayank R.en_US
dc.date.accessioned2020-10-16T07:58:16Z
dc.date.available2020-10-16T07:58:16Z
dc.date.issued2019-08
dc.description.abstractBackground: PIH, a pregnancy-specific disorder, is one of the major causes of maternal and perinatal morbidity and mortality worldwide.PIH and fetal growth restriction are important causes of perinatal and maternal morbidity and mortility.Methods: Hundred Indian pregnant women in their second trimester (13-20 weeks) and in their late second trimester (24-28 weeks) investigated for their serum β-hCG level and uterine artery Doppler studies respectively, attending OPD/IPD in Sir T. hospital, Bhavnagar from June 2014 to June 2015.Results: There is no clinical significance between parity and occurrence of PIH (p=0.2) and FGR (p=0.7). Out of 77 patients with their β hCG level ≤2 MoM, 2 patients (2.59%) developed PIH and FGR. And from 12 patients with their β hCG level ≥2 MoM 10 patients (80%) developed PIH and FGR which is highly significant (p<0.001). The study establishes the validity of beta HCG as a predictor of PIH and FGR with the sensitivity of 83.3%, specificity of 97.5%.Conclusions: This study can be concluded by there is a strong association between high maternal serum ß-hCG level, abnormal uterine Doppler studies with predicting adverse outcome of pregnancy like PIH and FGR. There is also a good association between high maternal serum ß-hCG level and rising severity of the disease.en_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, Government Medical College, Bhavnagar, Gujarat, Indiaen_US
dc.identifier.citationSheth Vishal S., Nakum Kanaklata D., Patel Mehul D., Lunagariya Mayank R.. Maternal serum βhCG level and uterine artery doppler studies as predictors of pregnancy induced hypertension and intra uterine growth restriction: a prospective study. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2019 Aug; 8(8): 3357-3361en_US
dc.identifier.issn2320-1770
dc.identifier.issn2320-1789
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/206973
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber8en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-1770.ijrcog20193565en_US
dc.subjectPIHen_US
dc.subjectSerum B-hcgen_US
dc.subjectUterine artery Doppleren_US
dc.titleMaternal serum βhCG level and uterine artery doppler studies as predictors of pregnancy induced hypertension and intra uterine growth restriction: a prospective studyen_US
dc.typeJournal Articleen_US
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