Angiographic follow-up of genous bioengineered stent in acute myocardial infarction (GENAMI)-a pilot study.

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dc.contributor.authorKaul, Upendraen_US
dc.contributor.authorBhatia, Vineeten_US
dc.contributor.authorGhose, Tapanen_US
dc.contributor.authorGupta, Ripenen_US
dc.contributor.authorKachru, Ranjanen_US
dc.contributor.authorSingh, Gyantien_US
dc.date.accessioned2008-11-12en_US
dc.date.accessioned2009-05-27T04:24:35Z
dc.date.available2008-11-12en_US
dc.date.available2009-05-27T04:24:35Z
dc.date.issued2008-11-12en_US
dc.description.abstractOBJECTIVE: GENAMI, an angiographic follow-up study was undertaken to evaluate the safety and efficacy of a new generation endothelial progenitor cell (EPC) capture stent, GENOUS during primary angioplasty for ST-elevation myocardial infarction (MI). METHODS: Eleven consecutive patients with acute ST-elevation MI underwent primary percutaneous coronary intervention (PCI) using a bio-engineered GENOUS EPC stent. RESULTS: Procedural success was 100%. Ten patients who survived underwent a follow-up angiography at 8 months. There was no instance of stent thrombosis during the follow-up period up to 12 months. The quantitative angiographic (quantitative coronary analysis [QCA]) follow-up data showed a late loss at 8 months of 0.97 +/- 0.94 mm and the late loss index was 44.35 +/- 40.47% with angiographic restenosis seen in 5 of 10 patients (50%). One of these patients with provocable ischemia underwent repeat PCI. CONCLUSIONS: The QCA data of this study shows a high late loss with frequent angiographic restenosis during follow-up with this stent during primary PCI for acute STEMI. This observation, with important clinical implications, needs to be confirmed in larger studies.en_US
dc.description.affiliationFortis Hospitals, Vasant Kunj and NOIDA. ukaul@vsnl.comen_US
dc.identifier.citationKaul U, Bhatia V, Ghose T, Gupta R, Kachru R, Singh G. Angiographic follow-up of genous bioengineered stent in acute myocardial infarction (GENAMI)-a pilot study. Indian Heart Journal. 2008 Nov-Dec; 60(6): 532-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/4797
dc.language.isoengen_US
dc.source.urihttps://indianheartjournal.comen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAngioplasty, Transluminal, Percutaneous Coronaryen_US
dc.subject.meshCoronary Angiographyen_US
dc.subject.meshCoronary Restenosis --prevention & controlen_US
dc.subject.meshCoronary Thrombosis --prevention & controlen_US
dc.subject.meshEndothelial Cellsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMyocardial Infarction --prevention & controlen_US
dc.subject.meshPilot Projectsen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshStem Cellsen_US
dc.subject.meshStentsen_US
dc.titleAngiographic follow-up of genous bioengineered stent in acute myocardial infarction (GENAMI)-a pilot study.en_US
dc.typeJournal Articleen_US
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