Evaluation of a hepatitis B vaccination program in Chiang Mai, Thailand.

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dc.contributor.authorJutavijittum, Prapanen_US
dc.contributor.authorJiviriyawat, Yupaen_US
dc.contributor.authorYousukh, Amnaten_US
dc.contributor.authorHayashi, Shigekien_US
dc.contributor.authorToriyama, Kanen_US
dc.date.accessioned2009-05-27T15:08:37Z
dc.date.available2009-05-27T15:08:37Z
dc.date.issued2005-01-24en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractChiang Mai is a province in northern Thailand that started a vaccination program for hepatitis B virus (HBV) infection in 1989. In this paper, we report the long-term efficacy of this program. Of children aged 4-9 years, 65.7% had a complete course and 3.8% had an incomplete vaccination course. Urban schoolchildren had higher percentage of HB vaccination than rural schoolchildren (89.1% vs 46.9% for the complete course, p < 0.001). The overall prevalence rate of HBsAg in Chiang Mai schoolchildren was 1.2%, with no significant differences between gender (p = 0.496) and school areas (p = 0.477). Anti-HBc antibodies were detected in 6.9% of children. Overall, 26.2% of children had protective levels of anti-HBs antibodies (> 10.0 mlU/ml), and 11.2% had low levels of these antibodies (1.0-9.9 mlU/ml). Compared to previous reports, our results show a lower percentage of anti-HBs antibodies, 33.8% of children age 4 years had protective anti-HBs antibodies, dropping to 18.4% by age 9 years. Among those anti-HBs seropositive, 9.1% were anti-HBc positive, indicating a natural infection with HBV. We found a small number of children, despite adequate immunization, developed HBV infection.en_US
dc.description.affiliationDepartment of Pathology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. pjutavij@mail.med.cmu.ac.then_US
dc.identifier.citationJutavijittum P, Jiviriyawat Y, Yousukh A, Hayashi S, Toriyama K. Evaluation of a hepatitis B vaccination program in Chiang Mai, Thailand. The Southeast Asian Journal of Tropical Medicine and Public Health. 2005 Jan; 36(1): 207-12en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/32025
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/2005_36_1/35-3376.pdfen_US
dc.subject.meshAntibodies, Viral --blooden_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshEndemic Diseases --prevention & controlen_US
dc.subject.meshFemaleen_US
dc.subject.meshHepatitis B --epidemiologyen_US
dc.subject.meshHepatitis B Vaccines --supply & distributionen_US
dc.subject.meshHepatitis B virus --immunologyen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunization Programs --standardsen_US
dc.subject.meshMaleen_US
dc.subject.meshPrevalenceen_US
dc.subject.meshProgram Evaluationen_US
dc.subject.meshRural Healthen_US
dc.subject.meshThailand --epidemiologyen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshUrban Healthen_US
dc.titleEvaluation of a hepatitis B vaccination program in Chiang Mai, Thailand.en_US
dc.typeEvaluation Studiesen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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