Study of Serum Uric Acid Level in Patients with Systemic-Essential Hypertension in the Context of New 2017 ACC/AHA High Blood Pressure Clinical Practice Guideline.

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dc.contributor.authorGhosh Atanuen_US
dc.contributor.authorPal, Debasishen_US
dc.contributor.authorDebbarma, Sagar Samraten_US
dc.contributor.authorChakraborty, Pranabeshen_US
dc.date.accessioned2020-11-18T10:18:50Z
dc.date.available2020-11-18T10:18:50Z
dc.date.issued2020-02
dc.description.abstractHypertension poses a challenge to public health as well as to the medical science. Final metabolite of purine in humans is uric acid, increased serum level of which is associated with cardio-renal risk, although serum uric acid (SUA) level appears to have different effects on blood pressure (BP), depending on level and how long subjects were exposed. We wanted to study the association between hyperuricemia and hypertension, in various aspects, in the context of new 2017 ACC/ AHA High Blood Pressure Clinical Practice Guidelines.METHODSThe study was conducted in a tertiary care hospital, Agartala, Tripura. It is a case control study. SUA estimation was in 160 hypertensive patients and 160 normotensive controls, by using uricase method. SPSS version 24 was used for data entry and analysis. Chi square test and unpaired t test were used, wherever applicable.RESULTSOut of 320 subjects, who were included in the study, 160 subjects were hypertensive and 160 subjects were normotensive. There was strong association between hypertension and hyperuricemia. Hyperuricemia is more common in males and in patients with stage II hypertension.CONCLUSIONSThe association between hyperuricemia and hypertension, has long been recognized. It remains unresolved whether the association of high uric acid level with high blood pressure is solely because of the underlying renal and metabolic abnormalities. Association of hyperuricemia and hypertension indicated that, hyperuricemia might be a target for the proposed therapeutic evaluation for the prevention of hypertension and provided impetus for the future design research work including interventional studies.en_US
dc.identifier.affiliationsDepartment of Medicine, Agartala Government Medical College, G. B. Pant Hospital, Kunjaban, Agartala, Tripura, Indiaen_US
dc.identifier.affiliationsDepartment of Medicine, Agartala Government Medical College, G. B. Pant Hospital, Kunjaban, Agartala, Tripura, Indiaen_US
dc.identifier.affiliationsDepartment of Medicine, Agartala Government Medical College, G. B. Pant Hospital, Kunjaban, Agartala, Tripura, Indiaen_US
dc.identifier.affiliationsDepartment of Medicine, Agartala Government Medical College, G. B. Pant Hospital, Kunjaban, Agartala, Tripura, India.en_US
dc.identifier.citationGhosh Atanu, Pal Debasish, Debbarma Sagar Samrat, Chakraborty Pranabesh. Study of Serum Uric Acid Level in Patients with Systemic-Essential Hypertension in the Context of New 2017 ACC/AHA High Blood Pressure Clinical Practice Guideline.. Journal of Evolution of Medical and Dental Sciences. 2020 Feb; 9(6): 363-367en_US
dc.identifier.issn2278-4802
dc.identifier.issn2278-4748
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/215353
dc.languageenen_US
dc.publisherAkshantala Enterprises Private Limiteden_US
dc.relation.issuenumber6en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org//10.14260/jemds/2020/82en_US
dc.subjectSerum Uric Aciden_US
dc.subjectHyperuricemiaen_US
dc.subjectHypertensionen_US
dc.subject2017 ACC/ AHA High Blood Pressure Clinical Practice Guidelineen_US
dc.subjectCardiovascular diseaseen_US
dc.subjectHypertensiveen_US
dc.subjectNormotensiveen_US
dc.titleStudy of Serum Uric Acid Level in Patients with Systemic-Essential Hypertension in the Context of New 2017 ACC/AHA High Blood Pressure Clinical Practice Guideline.en_US
dc.typeJournal Articleen_US
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