Seroprevalence of Covid-19 infection among healthcare workers: A study from a tertiary care hospital in the National Capital Region of India

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dc.contributor.authorKATARIA, SUSHILAen_US
dc.contributor.authorDESWAL, VIKASen_US
dc.contributor.authorGUPTA, VAIBHAVen_US
dc.contributor.authorPHOGAT, RASHMIen_US
dc.contributor.authorSARMA, SMITAen_US
dc.contributor.authorSAXENA, RENUen_US
dc.contributor.authorALAM, SAZIDen_US
dc.contributor.authorTREHAN, NARESHen_US
dc.contributor.authorKUMAR, KULDEEPen_US
dc.contributor.authorSINGH, PADAMen_US
dc.contributor.authorSHARMA, POOJAen_US
dc.contributor.authorSINGH, MANISHen_US
dc.contributor.authorDUTT, ROHITen_US
dc.date.accessioned2023-06-27T08:32:44Z
dc.date.available2023-06-27T08:32:44Z
dc.date.issued2022-08
dc.description.abstractBACKGROUND Seroprevalence studies on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can provide information on the target populations for vaccination. We aimed to evaluate the seroprevalence among healthcare workers (HCWs) at our tertiary care institution and to identify parameters that may affect it. METHOD We assessed seroprevalence of SARS-CoV-2 by the chemiluminescence immunoassay test among 3258 HCW in our hospital and evaluated as per gender, age, their previous Covid-19 diagnosis, role in hospital and type/risk of exposure. RESULTS Of 3258 participants, 46.2% (95% CI 44.4%– 47.9%) were positive for SARS-CoV-2 IgG antibodies (i.e. IgG ?15 AU/ml). Higher seroprevalence was seen in non-clinical HCWs (50.2%) than in clinical HCWs (41.4%, p=0.0001). Furthermore, people with a history of Covid-19 were found to have significantly higher antibody levels (p=0.0001). Among the HCWs, doctors and nurses had lower relative risk (RR) of acquiring Covid-19 infection (RR=0.82; 95% CI 0.76–0.89) compared to non-clinical HCWs. CONCLUSION Seroprevalence in HCWs at our hospital was 46.2%. Clinical HCWs had lower seroprevalence compared to non-clinical HCWs. Previous history of Covid-19 almost doubled the seropositivity, particularly in those with current infection.en_US
dc.identifier.affiliationsDepartment of Internal Medicine, Medanta–The Medicity, Sector-38, Gurugram 122001, Haryana, Indiaen_US
dc.identifier.affiliationsDepartment of Microbiology, Medanta–The Medicity, Sector-38, Gurugram 122001, Haryana, Indiaen_US
dc.identifier.affiliationsDepartment of Laboratory Medicine, Medanta–The Medicity, Sector-38, Gurugram 122001, Haryana, Indiaen_US
dc.identifier.affiliationsMedanta–The Medicity, Sector-38, Gurugram 122001, Haryana, Indiaen_US
dc.identifier.affiliationsMedanta Institute of Education and Research, Gurugram, Haryana, Indiaen_US
dc.identifier.affiliationsSchool of Medical and Allied Sciences, GD Goenka University, Gurugram, Haryana, Indiaen_US
dc.identifier.citationKATARIA SUSHILA, DESWAL VIKAS, GUPTA VAIBHAV, PHOGAT RASHMI, SARMA SMITA, SAXENA RENU, ALAM SAZID, TREHAN NARESH, KUMAR KULDEEP, SINGH PADAM, SHARMA POOJA, SINGH MANISH, DUTT ROHIT. Seroprevalence of Covid-19 infection among healthcare workers: A study from a tertiary care hospital in the National Capital Region of India. The National Medical Journal of India. 2022 Aug; 35(4): 219-220en_US
dc.identifier.issn0970-258X
dc.identifier.issn2583-150X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/218212
dc.languageenen_US
dc.publisherAll India Institute of Medical Sciencesen_US
dc.relation.issuenumber4en_US
dc.relation.volume35en_US
dc.source.urihttps://doi.org/10.25259/NMJI_345_21en_US
dc.titleSeroprevalence of Covid-19 infection among healthcare workers: A study from a tertiary care hospital in the National Capital Region of Indiaen_US
dc.typeJournal Articleen_US
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