Topical sulindac therapy in diabetic senile cataracts: cataract-IV.

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dc.contributor.authorSharma, Y Ren_US
dc.contributor.authorVajpayee, R Ben_US
dc.contributor.authorBhatnagar, Ren_US
dc.contributor.authorMohan, Men_US
dc.contributor.authorAzad, R Ven_US
dc.contributor.authorKumar, Men_US
dc.contributor.authorNath, Ren_US
dc.date.accessioned1989-07-01en_US
dc.date.accessioned2009-05-29T08:56:41Z
dc.date.available1989-07-01en_US
dc.date.available2009-05-29T08:56:41Z
dc.date.issued1989-07-01en_US
dc.description.abstractSulindac, a non-steroidal anti-inflammatory drug has been found to be a potent inhibitor of enzyme aldose reductase. We used sulindac topically in diabetic senile cataract patients to note if it effects the progression of cataracts. More of sulindac treated eyes maintained initial vision and fewer eyes had visual loss of up to two lines or more as compared to control eyes. The extent and density of different opacities showed less progression in sulindac treated eyes but it was not statistically significant except that the ophthalmoscopically observed density of opacity showed statistically very significant lesser mean increase in sulindac treated eyes. We suggest that sulindac is a potential drug which should be further evaluated in large double blind photodocumented studies in diabetic senile cataracts.en_US
dc.identifier.citationSharma YR, Vajpayee RB, Bhatnagar R, Mohan M, Azad RV, Kumar M, Nath R. Topical sulindac therapy in diabetic senile cataracts: cataract-IV. Indian Journal of Ophthalmology. 1989 Jul-Sep; 37(3): 127-33en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/71044
dc.language.isoengen_US
dc.source.urihttps://www.ijo.inen_US
dc.subject.meshAdministration, Topicalen_US
dc.subject.meshAgeden_US
dc.subject.meshAgingen_US
dc.subject.meshCataract --complicationsen_US
dc.subject.meshDiabetes Complicationsen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSulindac --administration & dosageen_US
dc.titleTopical sulindac therapy in diabetic senile cataracts: cataract-IV.en_US
dc.typeClinical Trialen_US
dc.typeControlled Clinical Trialen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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