Occurrence of colonization factor antigens I & II in enterotoxigenic Escherichia coli associated diarrhoea in Iran & correlation with severity of disease.

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dc.contributor.authorKatouli, Men_US
dc.contributor.authorShokouhi, Fen_US
dc.contributor.authorFarhoudi-Moghaddam, A Aen_US
dc.contributor.authorAmini, Sen_US
dc.date.accessioned1992-05-01en_US
dc.date.accessioned2009-05-27T07:08:39Z
dc.date.available1992-05-01en_US
dc.date.available2009-05-27T07:08:39Z
dc.date.issued1992-05-01en_US
dc.description.abstractThe occurrence of colonization factor antigens I and II (CFA/I and II) and type 1 somatic pili was investigated in 197 enterotoxigenic Esch. coli (ETEC) isolated from 197 patients of diarrhoea (aged under 3 yr) during February 1985 to March 1986 in Tehran, Iran. Among ETEC strains, 154 strains were heat-stable enterotoxin (ST) producers, 27 strains were heat-labile enterotoxin (LT) producers, and 16 strains produced both toxins. Sixty five (33%) strains showed mannose-resistant haemagglutination (MRHA) of human and/or bovine erythrocytes; of these, 51 (86%) strains were positive for CFA/I and II. Seventy one (36%) strains also exhibited type 1 somatic pili. CFA/I was found in 4 (15%) LT producing, 24 (16%) ST producing, and 2 (13%) LT/ST producing strains. In contrast, CFA/II was only found in ST producing strains (17 strains) and those producing both toxins (4 strains). Patients having CFAs-positive ETEC strains had a significantly (P less than 0.001) higher number of stool evacuation per day and a longer duration of diarrhoea than those having CFAs-negative strains. Fifty nine patients had mixed infections of ETEC strains and other enteropathogens. CFA/I or II (CFAs)-positive and CFAs-negative ETEC strains were found in 17 and 42 patients with mixed infections respectively. The mean number of stool evacuations per day was much higher in patients with ETEC and rotavirus than those with only ETEC infection (P less than 0.001). However, severity of the disease was not affected by the presence or absence of CFA/I or II in ETEC strains found in these patients.en_US
dc.description.affiliationMicrobiology Department, Pasteur Institute of Iran, Tehran.en_US
dc.identifier.citationKatouli M, Shokouhi F, Farhoudi-Moghaddam AA, Amini S. Occurrence of colonization factor antigens I & II in enterotoxigenic Escherichia coli associated diarrhoea in Iran & correlation with severity of disease. Indian Journal of Medical Research. 1992 May; 95(): 115-20en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/19483
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAgglutination Testsen_US
dc.subject.meshAntigens, Bacterial --analysisen_US
dc.subject.meshBacterial Toxins --biosynthesisen_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshDiarrhea --microbiologyen_US
dc.subject.meshDiarrhea, Infantile --microbiologyen_US
dc.subject.meshEnterotoxins --biosynthesisen_US
dc.subject.meshEscherichia coli --immunologyen_US
dc.subject.meshEscherichia coli Infections --microbiologyen_US
dc.subject.meshEscherichia coli Proteinsen_US
dc.subject.meshFimbriae Proteinsen_US
dc.subject.meshFimbriae, Bacterialen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshIranen_US
dc.titleOccurrence of colonization factor antigens I & II in enterotoxigenic Escherichia coli associated diarrhoea in Iran & correlation with severity of disease.en_US
dc.typeJournal Articleen_US
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