Use of Intravenous Immunoglobulin (IVIg)

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Date
2010-01-06
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Vajira Medical Journal
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Abstract Use of Intravenous Immunoglobulin (IVIg) Panadda Suwan MD Department of Pediatrics, BMA Medical College and Vajira Hospital           Initially used as a replacement therapy for immunodeficiency diseases, intravenous immunoglobulin (IVIg) is now widely used for a number of autoimmune and inflammatory diseases. The mechanisms of action of IVIg are several, it can modulate an immune reaction at the level of T cells, B cells, macrophages, the complement cascade and the cytokine network. Given the potential risks and cost-effectiveness of IVIg, careful consideration of the indications and administration of IVIg is warranted. Vajira Med J 2009 ; 53 : 89 - 100
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Vajira Medical Journal; Vol. 53 No. 1 January - April 2009; 89-100