Comparing the Clinical Efficacy of Mifepristone and Misoprostol Treatment Protocol for Induction of Parturition in Bitches
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Date
2021-12
Journal Title
Journal ISSN
Volume Title
Publisher
Reproduction Biology and Genetics Society
Abstract
Successful management of parturition induction is a challenging task in canine. This study made to assess the efficacy of antiprogestagen mifepristone and prostaglandin misoprostol in induction of parturition in bitches. Total of 11 pregnant bitches with gestational age of more than 62 days confirmed by ultrasound scanning and not showing any sings of initiation of parturition were selected. Induction of parturition was initiated by mifepristone (3 mg/ kg b wt PO) twice a day or a combination of mifepristone (3 mg/kg b wt PO) and misoprostol (200 ?g for < 20 kg, 400 ?g for > 20 kg b wt, i/vg) 12 h after second dose of mifepristone. The combination of both drugs mifepristone and misoprostol was more effective for parturition induction.
Description
Keywords
Mifeioristone, Misoprostol, Pregnancy termination
Citation
Kumar Devender, Nain Satish, Badsiwal Dinesh Kumar, Singh Narendra, Choudhary Archana, Panghal Sanjay. Comparing the Clinical Efficacy of Mifepristone and Misoprostol Treatment Protocol for Induction of Parturition in Bitches . Theriogenology insight . 2021 Dec; 11(2): 33-36