Serum CPK levels in schizophrenics and their first degree relatives.

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dc.contributor.authorKumar, Aen_US
dc.contributor.authorUpadhyaya, G Len_US
dc.contributor.authorTrivedi, J Ken_US
dc.date.accessioned1984-04-01en_US
dc.date.accessioned2009-06-01T07:30:00Z
dc.date.available1984-04-01en_US
dc.date.available2009-06-01T07:30:00Z
dc.date.issued1984-04-01en_US
dc.description.abstractBlood samples of 20 schizophrenic patients, 20 of their first degree relatives and 43 normal subjects, both male and female, were taken and serum CPK estimation was done by using colorimetric sigma procedure. The schizophrenics and their 1st degree relatives had shown a significantly higher mean +/- S.D. CPK levels of 31.25 +/- 21.6 and 16.15 +/- 4.7 Sigma Units respectively as compared to 11.16 +/- 3.38 Sigma Units in normals (Cal. t = 5.73, tab. t = 1.65 at df = 61 and P less than 05). A significant difference between the CPK levels of male and female of the three groups was found (P less than .05). The males of normal, Schizophrenics and 1st degree relatives had significantly higher mean +/- S.D. CPK levels of 12.65 +/- 3.05, 47.4 +/- 18.73 and 19.5 +/- 1.93 Sigma Units respectively as compared to levels of 9.45 +/- 2.94, 15.10 +/- 4.33 and 12.71 +/- 2.47 sigma units in females of the corresponding three groups (P less than .05). Males of the patients and 1st degree relatives had shown higher levels than the females. A highly significant and positive correlation was found between the mean serum CPK levels of Schizophrenic patients and their 1st degree relatives (Correlation coefficient (gamma yx) = 0.79).en_US
dc.identifier.citationKumar A, Upadhyaya GL, Trivedi JK. Serum CPK levels in schizophrenics and their first degree relatives. Indian Journal of Physiology and Pharmacology. 1984 Apr-Jun; 28(2): 128-32en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/108201
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshCreatine Kinase --blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshSchizophrenia --enzymologyen_US
dc.subject.meshSex Factorsen_US
dc.titleSerum CPK levels in schizophrenics and their first degree relatives.en_US
dc.typeJournal Articleen_US
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