Potency assay of antivenom: Failure of Indian (serum institute) antivenom to neutralise Russell's viper (Daboia russelli siamensis) venom of Myanmar

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dc.contributor.authorTun Peen_US
dc.contributor.authorAye Aye Myinten_US
dc.contributor.authorKyi May Htween_US
dc.date.accessioned2009-06-30T09:02:33Z
dc.date.available2009-06-30T09:02:33Z
dc.date.created1996-08-01en_US
dc.date.issued1996-08-01en_US
dc.description.abstractNeutralisation of biological properties of Russell's viper (Daboia russelli siamensis) venom of Tharyarwady by a monospecific antivenom of Myanmar (DN 86608B ex. 4/92) and a polyspecific antivenom of Serum Institute of India (Sii) (batch 109 exp. 4/96) was carried out according to WHO standard tests of neutralising activity. Neutralising potency of Myanmar antivenom was superior to the Indian antivenom and the latter required 16-126 times more antivenom than the former in neutralising haemorrhagic, necrotic, lethality, defibrinogenating and capillary permeability increasing activities of the venom. In immunodiffusion and immunoblotting experiments fewer bands were detected in both. It is concluded that the Indian antivenom (Sii) will be less effective in treating Russell's viper bite cases of Myanmar.en_US
dc.identifier.citationTun Pe, Aye Aye Myint, Kyi May Htwe. Potency assay of antivenom: Failure of Indian (serum institute) antivenom to neutralise Russell's viper (Daboia russelli siamensis) venom of Myanmar. Myanmar Health Sciences Research Journal. 1996; 8(2): 59-61en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/127085
dc.subject.meshViper Venomen_US
dc.subject.meshAntiveninsen_US
dc.subject.meshSnake Biteen_US
dc.subject.meshNeutralization Testsen_US
dc.subject.meshRussell's Viperen_US
dc.subject.meshMyanmaren_US
dc.titlePotency assay of antivenom: Failure of Indian (serum institute) antivenom to neutralise Russell's viper (Daboia russelli siamensis) venom of Myanmaren_US
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