Neonatal cholestasis syndrome: Indian scene.

dc.contributor.authorYachha, S Ken_US
dc.contributor.authorMohindra, Sen_US
dc.date.accessioned1999-11-02en_US
dc.date.accessioned2009-05-30T10:56:20Z
dc.date.available1999-11-02en_US
dc.date.available2009-05-30T10:56:20Z
dc.date.issued1999-11-02en_US
dc.description7 references.en_US
dc.description.abstractNeonatal cholestasis syndrome (NCS) in India has largely remained ignored. Three questions need to be addressed: (a) What is known about NCS in India (b) Where do we stand and (c) What needs to be done? Current data on etiology of NCS indicates that biliary atresia contributes to about 40% of all NCS cases. There is considerable delay in the referral of patients to appropriate centres for management. A delay of 120.8 +/- 60.5 days in biliary atresia and 65.9 +/- 39.2 days in neonatal hepatitis were documented. Biliary atresia cases need to be diagnosed and operated by eight weeks of age so as to have the best results. Delayed referral after 3 months of age, not only bring down the success rate considerably but also adversely affect the management with regard to surgical procedures, nutritional support, control of ascites and finally the cost. Cirrhosis rapidly develops in children with biliary atresia. At this stage the only option left is liver transplantation. An important obstacle in the care of infants with NCS is the misconception of jaundice in newborns. This needs to be handled at a professional level in the training of undergraduates and postgraduates and the lay public. Public awareness campaigns like "Yellow Alert" may be useful in this direction.en_US
dc.description.affiliationDepartment of Gastroenterology (Pediatric GE), Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow.en_US
dc.identifier.citationYachha SK, Mohindra S. Neonatal cholestasis syndrome: Indian scene. Indian Journal of Pediatrics. 1999 ; 66(1 Suppl): S94-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/79163
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshCholestasis --epidemiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshMaleen_US
dc.subject.meshPrognosisen_US
dc.subject.meshRisk Assessmenten_US
dc.subject.meshRisk Factorsen_US
dc.titleNeonatal cholestasis syndrome: Indian scene.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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