Clinicopathological study of acute renal failure following viperine snake bite.

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dc.contributor.authorMerchant, M Ren_US
dc.contributor.authorKhanna, U Ben_US
dc.contributor.authorAlmeida, A Fen_US
dc.contributor.authorAcharya, V Nen_US
dc.contributor.authorMittal, B Ven_US
dc.date.accessioned1989-07-01en_US
dc.date.accessioned2009-05-30T21:28:12Z
dc.date.available1989-07-01en_US
dc.date.available2009-05-30T21:28:12Z
dc.date.issued1989-07-01en_US
dc.description.abstractFifty patients of acute renal failure following Viperine snake bite were studied. Oliguria (100%), local swelling (48%) and bleeding tendencies (42%) were the predominant clinical features encountered. Of the 25 patients in whom detailed coagulation studies were done, 24 patients had disseminated intravascular coagulation (DIC) and 1 had primary fibrinolysis. DIC was commoner with Russell's viper bite (62%) in comparison to Echis carinatus bites (40%). Renal histology obtained in 29 cases revealed tubular necrosis (35%), cortical necrosis (24%) tubular degeneration (17%) and glomerular changes (17%). Ballooning of glomerular capillaries (59%), splitting of glomerular basement membrane (40.7%), swelling of endothelial cells (29.6%), and focal proliferation of mesangial cells (17%) were the significant glomerular changes encountered. 20 (40%) patients succumbed, DIC (50%), irreversible shock (30%) and septicaemia (20%) being the immediate causes of death. Development of oliguria within 24 hours of snake bite and cortical necrosis were associated with higher mortality.en_US
dc.identifier.citationMerchant MR, Khanna UB, Almeida AF, Acharya VN, Mittal BV. Clinicopathological study of acute renal failure following viperine snake bite. Journal of the Association of Physicians of India. 1989 Jul; 37(7): 430-3en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/88648
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshFemaleen_US
dc.subject.meshGlomerular Mesangium --pathologyen_US
dc.subject.meshHumansen_US
dc.subject.meshKidney Failure, Acute --chemically induceden_US
dc.subject.meshKidney Tubular Necrosis, Acute --chemically induceden_US
dc.subject.meshMaleen_US
dc.subject.meshViper Venoms --poisoningen_US
dc.titleClinicopathological study of acute renal failure following viperine snake bite.en_US
dc.typeJournal Articleen_US
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