Olanzapine overdose presenting with pinpoint pupils and semi consciousness: a case report
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Date
2013-07
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Psychiatric Society
Abstract
Background: Olanzapine is an atypical antipsychotic widely prescribed in schizophrenia patients because of
its better tolerability. Clinical picture due to olanzapine over dosage can be confusing in the emergency
department. Also often the patient would be drowsy to provide adequate information regarding the method of
self harm attempt.
Case description: We are reporting a case of olanzapine over dosage which presented to the emergency
department with pin point pupils, lacrimation, and hypotension and semi conscious state.
Discussion: Organophosphorous poison consumption is one of the common methods of suicide in rural south
Indian setting which presents with miosis, respiratory depression and unconsciousness. Pontine hemorrhage
is one more condition apart from opiod intoxication which presents with pin point pupils and altered mental
status.
Conclusion: We attributed olanzapine over dosage as the cause of pin point pupils, lacrimation and drowsiness
in our case as other causes were excluded.
Description
Keywords
Olanzapine, Pin Point Pupils, Lacrimation
Citation
Angothu Hareesh, Bandari Jagdeesh Babu, Soma Madhava Rao. Olanzapine overdose presenting with pinpoint pupils and semi consciousness: a case report. Andhra Pradesh Journal of Psychological Medicine. 2013 Jul-Dec; 14(2): 171-173