Adherence and Cost Effectivity of Home-Based Prophylaxis Over Institutionalized Prophylaxis in Patients with Hemophilia

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dc.contributor.authorDutta, Anupamen_US
dc.contributor.authorBoruah, Dipjyotien_US
dc.contributor.authorBoruah, Angshumanen_US
dc.contributor.authorDas, Arijiten_US
dc.date.accessioned2023-07-21T11:28:16Z
dc.date.available2023-07-21T11:28:16Z
dc.date.issued2023-01
dc.description.abstractPurpose: Home-based prophylaxis in hemophilia facilitates the treatment of patients with hemophilia (PwH) at home resulting in an improved quality of life, experiencing less pain and greater flexibility in daily activities. This literature studies the cost effectivity and adherence to prophylaxis treatment after the implementation of home-based prophylaxis therapy in PwH registered under the Hemophilia Treatment Centre (HTC) of Assam Medical College and Hospital. Materials and Methods:?PwH and their parents were advised for self/home infusion after being trained by a medical professional for 6 months. Data were collected on the skip in prophylaxis treatment by PwH and their traveling cost to access the prophylaxis treatment before and after the implementation of home infusion, through questionnaire and telephonic interview. Results:?The mean number of days of skip in prophylaxis was significantly reduced from 25 (±11) to 4 (±2) days after implementation of home infusion. The mean transportation cost was also found to be significantly decreased from Rs. 3297 (±2251) to 440 (±279). Before home/self-infusion, 77% of the registered PwH were found to skip prophylaxis doses more than 12 times a year but after home infusion, no PwH were found to skip more than 12 doses a year. Conclusion:?Home therapy facilitates the PwH to strictly adhere to the prophylaxis regime significantly reducing the skipping of doses to be administered to the PwH. The risks of regular traveling and the burden of transportation expenditure to avail the prophylaxis treatment was also found to be reduced significantly.en_US
dc.identifier.affiliationsDepartment of Medicine, Assam Medical College and Hospital, Dibrugarh, Assam, Indiaen_US
dc.identifier.affiliationsDepartment of Medicine, Assam Medical College and Hospital, Dibrugarh, Assam, Indiaen_US
dc.identifier.affiliationsDepartment of Medicine, Assam Medical College and Hospital, Dibrugarh, Assam, Indiaen_US
dc.identifier.affiliationsDepartment of Medicine, Assam Medical College and Hospital, Dibrugarh, Assam, Indiaen_US
dc.identifier.citationDutta, Anupamen_US
dc.identifier.citationBoruah, Dipjyotien_US
dc.identifier.citationBoruah, Angshumanen_US
dc.identifier.citationDas, Arijit. Adherence and Cost Effectivity of Home-Based Prophylaxis Over Institutionalized Prophylaxis in Patients with Hemophilia. Annals of the National Academy of Medical Sciences. 2023 Jan; 59(1): 21-26en_US
dc.identifier.issn0379-038X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/220216
dc.languageenen_US
dc.publisherThieme Medical and Scientific Publishers Pvt. Ltden_US
dc.relation.issuenumber1en_US
dc.relation.volume59en_US
dc.source.urihttps://doi.org/10.1055/s-0042-1760083en_US
dc.subjecthome careen_US
dc.subjectself-infusionen_US
dc.subjectprophylaxis treatmenten_US
dc.subjecteconomic and traveling burdenen_US
dc.titleAdherence and Cost Effectivity of Home-Based Prophylaxis Over Institutionalized Prophylaxis in Patients with Hemophiliaen_US
dc.typeJournal Articleen_US
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