Asymptomatic bacteriuria in pregnancy: what is the validity of urine sediment microscopy as a screening tool in a low resource setting?

dc.contributor.authorPolnaya, Rashmien_US
dc.contributor.authorBhandary, Amrithaen_US
dc.date.accessioned2020-10-16T08:05:09Z
dc.date.available2020-10-16T08:05:09Z
dc.date.issued2020-06
dc.description.abstractBackground: Asymptomatic bacteriuria in pregnancy should be screened and treated to reduce the risk of morbidity and mortality. Urine culture is the recommended test. In low resource setting with large patient load urine culture in all pregnant patients is not feasible. In this study authors have assessed the validity of urine microscopy in the screening of asymptomatic bacteriuria in pregnancy.Methods: Midstream clean catch urine specimen collected from 675 pregnant women was subjected to urine sediment microscopy and culture. It was considered screen positive if pus cells were >5/HPF. Asymptomatic bacteriuria was diagnosed if there were >/=100000 CFU of a single uropathogen per ml. Results obtained were statistically analysed for the prevalence of asymptomatic bacteriuria, sociodemographic and medical risk factors, causative organisms, antibiotic sensitivity and validity of urine sediment microscopy in detecting asymptomatic bacteriuria.Results: The incidence of asymptomatic bacteriuria in our study was 10.2%. The incidence was higher in the age group between 20-30 years, in gravida 3 and above, in upper lower and lower socioeconomic status, in women with hyperglycemia in pregnancy and anaemia. E. coli was the commonest bacterial isolate in culture positive cases. Bacterial isolates had poor sensitivity for Ampicillin, amoxicillin and nitrofurantoin and good sensitivity for cephalosporins and aminoglycosides. The sensitivity, specificity, positive and negative predictive values for urine microscopy was 43%, 85%, 25% and 93% respectively.Conclusions: This study shows poor sensitivity and positive predictive value and good specificity and negative predictive value.en_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, Kasturba Medical College, Mangaluru, Manipal Academy of Higher Education, Karnataka, Indiaen_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, AJ Institute of Medical Sciences, Mangaluru, Karnataka, Indiaen_US
dc.identifier.citationPolnaya Rashmi, Bhandary Amritha. Asymptomatic bacteriuria in pregnancy: what is the validity of urine sediment microscopy as a screening tool in a low resource setting?. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2020 Jun; 9(6): 2442-2445en_US
dc.identifier.issn2320-1770
dc.identifier.issn2320-1789
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/207767
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber6en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-1770.ijrcog20202326en_US
dc.subjectAsymptomatic bacteriuriaen_US
dc.subjectScreeningen_US
dc.subjectUrine cultureen_US
dc.subjectUrine microscopyen_US
dc.titleAsymptomatic bacteriuria in pregnancy: what is the validity of urine sediment microscopy as a screening tool in a low resource setting?en_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
ijrcog2020v9n6p2442.pdf
Size:
142.9 KB
Format:
Adobe Portable Document Format