Characterization of class 1 integrons with unusual 3' conserved region from Salmonella enterica isolates.

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dc.contributor.authorChuanchuen, Rungtipen_US
dc.contributor.authorKoowatananukul, Chailaien_US
dc.contributor.authorKhemtong, Sirintipen_US
dc.date.accessioned2009-05-27T15:54:54Z
dc.date.available2009-05-27T15:54:54Z
dc.date.issued2008-05-21en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractThe unusual 3' conserved sequence region of class 1 integrons was characterized in seven Salmonella isolates from swine and poultry. Three types of gene cassette arrays, aadA2-cmlA1-aadA1, sat-psp-aadA2-cm1A1-aadA1 and drfA12-orf-aadA2-cmlA1-aadA1, were found to be linked to a genetic organization qacH-IS440-sul3. All class 1 integrons were located on a conjugative plasmid that could be transferred to Escherichia coli. The results support the notion that the use of an antibiotic can select for resistance not only to that specific agent, but also to other unrelated antimicrobials including those that are no longer approved for use in food animal production.en_US
dc.description.affiliationFaculty of Veterinary Science, Chulalongkorn University, Pathumwan, Bangkok 10300, Thailand. rchuanchuen@yahoo.comen_US
dc.identifier.citationChuanchuen R, Koowatananukul C, Khemtong S. Characterization of class 1 integrons with unusual 3' conserved region from Salmonella enterica isolates. The Southeast Asian Journal of Tropical Medicine and Public Health. 2008 May; 39(3): 419-24en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/33970
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/2008_39_3/07-4237.pdfen_US
dc.subject.meshAnimalsen_US
dc.subject.meshConjugation, Geneticen_US
dc.subject.meshConserved Sequenceen_US
dc.subject.meshDrug Resistance, Multiple, Bacterial --geneticsen_US
dc.subject.meshEscherichia coli --drug effectsen_US
dc.subject.meshIntegrons --geneticsen_US
dc.subject.meshMicrobial Sensitivity Testsen_US
dc.subject.meshPolymerase Chain Reactionen_US
dc.subject.meshPoultryen_US
dc.subject.meshSalmonella enterica --drug effectsen_US
dc.subject.meshSequence Analysis, DNAen_US
dc.subject.meshSwineen_US
dc.titleCharacterization of class 1 integrons with unusual 3' conserved region from Salmonella enterica isolates.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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