Male gonadal function in Hodgkin's disease before and after treatment.

dc.contributor.authorDas, P Ken_US
dc.contributor.authorDas, B Ken_US
dc.contributor.authorSahu, D Cen_US
dc.contributor.authorMohanty, G Nen_US
dc.contributor.authorRath, R Nen_US
dc.date.accessioned1994-08-01en_US
dc.date.accessioned2009-05-30T23:38:12Z
dc.date.available1994-08-01en_US
dc.date.available2009-05-30T23:38:12Z
dc.date.issued1994-08-01en_US
dc.description.abstractTwenty eight histologically confirmed cases of Hodgkin's disease were evaluates with regard to libido, sperm count, FSH, LH and urinary ketosteroid levels, before and during different stages of chemotherapy along with testicular biopsy on 16 cases. Decrease in libido during therapy improved following treatment, 50% cases who were oligospermic before treatment became azospermic, Serum FSH levels increased significantly (p 0.001) during the course of treatment. There was no significant change in LH and urinary ketosteroid levels (p 0.05). Testicular biopsy, normal initially, showed germ cell aplasia and absence of spermatogenesis after therapy. Drug induced testicular change leads to sterility.en_US
dc.description.affiliationDept of Pathology, SCB Medical College, Cuttack.en_US
dc.identifier.citationDas PK, Das BK, Sahu DC, Mohanty GN, Rath RN. Male gonadal function in Hodgkin's disease before and after treatment. Journal of the Association of Physicians of India. 1994 Aug; 42(8): 604-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/90599
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.mesh17-Ketosteroids --urineen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshCombined Modality Therapyen_US
dc.subject.meshFollicle Stimulating Hormone --blooden_US
dc.subject.meshHodgkin Disease --metabolismen_US
dc.subject.meshHumansen_US
dc.subject.meshLibidoen_US
dc.subject.meshLuteinizing Hormone --blooden_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSperm Counten_US
dc.titleMale gonadal function in Hodgkin's disease before and after treatment.en_US
dc.typeJournal Articleen_US
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