Seminal profiles of lysosomal enzymes in normal and infertile men.

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dc.contributor.authorDandekar, S Pen_US
dc.contributor.authorHarikumar, Pen_US
dc.date.accessioned1997-04-01en_US
dc.date.accessioned2009-06-02T11:37:00Z
dc.date.available1997-04-01en_US
dc.date.available2009-06-02T11:37:00Z
dc.date.issued1997-04-01en_US
dc.description.abstractHuman seminal plasma is known to possess considerable proteolytic activity, much of which is associated with lysosomes. The activities of lysosomal hydrolases like alkaline proteinase, cathepsin-D, aryl-sulfatase and N-acetyl-beta-D-glucosaminidase in seminal plasma from randomly chosen infertile and vasectomised men have been compared. These enzymes have been implicated in the coagulation and liquefaction processes. The role of fructose and proteins in these processes has also been studied. The results indicate that cathepsin-D and aryl-sulfatase activity in infertile men were significantly lower than normo-spermic subjects. N-acetyl-beta-D-glucosaminidase was lowest in azoospermia suggesting that it could be used as a biochemical marker for azoospermia. Conversely, alkaline proteinase showed increased levels in all the infertile cases.en_US
dc.description.affiliationDept. of Biochemistry, Seth GS Medical College, Parel, Mumbai, India.en_US
dc.identifier.citationDandekar SP, Harikumar P. Seminal profiles of lysosomal enzymes in normal and infertile men. Journal of Postgraduate Medicine. 1997 Apr-Jun; 43(2): 33-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/116339
dc.language.isoengen_US
dc.source.urihttps://www.jpgmonline.comen_US
dc.subject.meshFructose --metabolismen_US
dc.subject.meshHumansen_US
dc.subject.meshInfertility, Male --enzymologyen_US
dc.subject.meshLysosomes --enzymologyen_US
dc.subject.meshMaleen_US
dc.subject.meshProteins --metabolismen_US
dc.subject.meshReference Valuesen_US
dc.subject.meshSemen --enzymologyen_US
dc.subject.meshSperm Counten_US
dc.titleSeminal profiles of lysosomal enzymes in normal and infertile men.en_US
dc.typeJournal Articleen_US
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