Atypical neuroleptic malignant syndrome. “Doing more harm than gain”.
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Date
2013-10
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Abstract
Neuroleptic malignant syndrome (NMS) a rare, idiosyncratic, and potentially fatal adverse reaction can be deceptive especially when the hallmark features are lacking. Most diagnostic criteria include fever and muscle rigidity, although NMS may present without either. Delirium, agitation and catatonia can be the earliest features of NMS and in acute care settings, concomitant use of sedatives and anti-psychotics by the attending clinicians may even obscure the sentinel signs of NMS and further aggravate the underlying insult. A strong clinical suspicion based on clinical history is crucial for early diagnosis and treatment and the strict adherence to the classical criteria of NMS may lead to a diagnostic delay and dire consequences for these patients and sometimes this delay can procure death.
Description
Keywords
Neuroleptic malignant syndrome, Idiosyncratic, Muscle rigidity
Citation
Bhat Khalid Javid, Pandita Kamal Kishore, Bhat Sanjay, Gupta Subhash Chander. Atypical neuroleptic malignant syndrome. “Doing more harm than gain”. International Journal of Research in Medical Sciences. 2013 Oct-Dec; 1(4): 601-603.