Chryseobacterium meningosepticum infections in a dialysis unit.

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dc.contributor.authorPerera, Shalinieen_US
dc.contributor.authorPalasuntheram, Cen_US
dc.date.accessioned2009-05-28T05:01:00Z
dc.date.available2009-05-28T05:01:00Z
dc.date.issued2004-06-01en_US
dc.descriptionThe Ceylon Medical Journal.en_US
dc.description.abstractBACKGROUND: Chryseobacterium species are Gram-negative bacteria with an unusual antibiotic profile. Chryseobacterium meningosepticum is the species most commonly encountered as a human pathogen. OBJECTIVES: To study the microbiological, clinical and therapeutic features of C. meningosepticum infections in patients on dialysis, at Sri Jayewardenepura General Hospital (Teaching) (SJGH), and to trace the source of infections. DESIGN: A retrospective descriptive study. SETTING: Dialysis unit of SJGH. PATIENT: population Patients who underwent long term haemodialysis (HD) and manual intermittent peritoneal dialysis (IPD) in the dialysis unit. METHODS: Clinical and microbiological records of patients with C. meningosepticum infections over a period of 2 years were reviewed retrospectively. Environmental screening was carried out to detect a possible source of infection. RESULTS: Thirty five episodes of infection due to C. meningosepticum in 33 patients on HD and IPD were detected. There were 30 episodes of peritonitis, four of bacteraemia and one of asymptomatic colonization of a PD catheter. Isolates were resistant to aminoglycosides, chephalosporins and aztreonam, and sensitive to cotrimoxazole, vancomycin and rifampicin. They showed variable sensitivity to imipenem and ciprofloxacin. All except one patient had a favourable outcome. C. meningosepticum was cultured from a sink in the dialysis unit, but the original source of the organism was not known. CONCLUSION: C. meningosepticum could be an important pathogen in a dialysis unit, and fluoroquinolones and vancomycin are effective as empiric therapy.en_US
dc.description.affiliationSri Jayewardenepura General Hospital (Teaching), Nugegoda, Sri Lanka. nhvn@sltnet.lken_US
dc.identifier.citationPerera S, Palasuntheram C. Chryseobacterium meningosepticum infections in a dialysis unit. The Ceylon Medical Journal. 2004 Jun; 49(2): 57-60en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/47797
dc.language.isoengen_US
dc.source.urihttps://www.infolanka.com/CMJhome/en_US
dc.subject.meshChryseobacterium --drug effectsen_US
dc.subject.meshCiprofloxacin --therapeutic useen_US
dc.subject.meshCross Infection --epidemiologyen_US
dc.subject.meshEquipment Contaminationen_US
dc.subject.meshFlavobacteriaceae Infections --drug therapyen_US
dc.subject.meshHemodialysis Units, Hospitalen_US
dc.subject.meshHospitals, Generalen_US
dc.subject.meshHospitals, Teachingen_US
dc.subject.meshHumansen_US
dc.subject.meshPeritoneal Dialysisen_US
dc.subject.meshPeritonitis --drug therapyen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSepsis --drug therapyen_US
dc.subject.meshSri Lanka --epidemiologyen_US
dc.subject.meshVancomycin --therapeutic useen_US
dc.titleChryseobacterium meningosepticum infections in a dialysis unit.en_US
dc.typeJournal Articleen_US
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