Prevalence of Coronary Risk Factors in Type 2 Diabetics without Manifestations of Overt Coronary Heart Disease.

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dc.contributor.authorAgarwal, A K
dc.contributor.authorSingla, Sweta
dc.contributor.authorSingla, S
dc.contributor.authorSingla, R
dc.contributor.authorLal, A
dc.contributor.authorWardhan, H
dc.contributor.authorYadav, Rajbala
dc.date.accessioned2012-12-03T06:35:03Z
dc.date.available2012-12-03T06:35:03Z
dc.date.issued2009-02
dc.description.abstractAims : To find the prevalence of cardiovascular risk factors in type-2 diabetics without manifestations of overt coronary heart disease and to estimate the prevalence of silent myocardial ischaemia in these patients. Methods : Seventy seven patients of type 2 diabetes were recruited for the study (one patient lost after recruitment; 76 completed the study). History and physical examination were recorded. Laboratory investigations included fasting and 2-hour post-prandial blood sugar, blood urea, serum creatinine, lipid profile, glycated haemoglobin, and microalbuminuria. Ultrasonographic scanning of the carotid arteries was performed to measure the carotid IMT. For identification of cases of silent ischaemia, treadmill test (TMT) was performed. Results : The study group was divided into a non-CAD group (n=54), and a silent CAD group (n=22). Twenty-two diabetics were found to have silent CAD as evidenced by a positive TMT result (28.9%). The prevalence of silent myocardial ischaemia was almost similar in both males and females. Serum LDL levels more than 140 mg% had a significant correlation with the prevalence of silent CAD (p=0.04). The difference in CCA-IMT values was found to be statistically significant between the silent CAD and non-CAD groups (p=0.019). Conclusion : High LDL level and greater carotid intima-media thickness are particularly important parameters that can predict if a patient of type 2 diabetes is at risk for silent ischaemia. A high carotid IMT is a surrogate and reliable marker of higher risk of CAD amongst type 2 diabetic patients, even in those without overt CAD. The study also underlines the utility of carotid IMT as a simple, non-invasive, safe, and cheap screening test for the assessment of risk of CAD in type 2 diabetics. ©en_US
dc.identifier.citationAgarwal A K, Singla Sweta, Singla S, Singla R, Lal A, Wardhan H, Yadav Rajbala. Prevalence of Coronary Risk Factors in Type 2 Diabetics without Manifestations of Overt Coronary Heart Disease. Journal of the Association of Physicians of India. 2009 Feb; 57(): 135-142.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/143537
dc.language.isoenen_US
dc.source.urihttps://www.japi.org/february_2009/O-3.htmlen_US
dc.subject.lcshPrevalence
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshCohort Studies
dc.subject.meshCoronary Disease --diagnosis
dc.subject.meshCoronary Disease --epidemiology
dc.subject.meshCross-Sectional Studies
dc.subject.meshDiabetes Mellitus, Type 2 --complications
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshRisk Factors
dc.titlePrevalence of Coronary Risk Factors in Type 2 Diabetics without Manifestations of Overt Coronary Heart Disease.en_US
dc.typeArticleen_US
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