Myelosuppression in breast cancer patients receiving postoperative radiation

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dc.contributor.authorPongsatorn Supaattagorn; Radiation Oncology Department, Ubonratchathani Cancer Centeren_US
dc.contributor.authorTawin Chottetanaprasith; Radiation Oncology Department, Ubonratchathani Cancer Centeren_US
dc.contributor.authorThanut Khuayjarernpanishk; Radiation Oncology Department, Ubonratchathani Cancer Centeren_US
dc.contributor.authorSirilak Ngoeiwikit; Radiation Oncology Outpatient Department, Ubonratchathani Cancer Centeren_US
dc.contributor.authorChuenchom Songyai; Radiation Oncology Outpatient Department, Ubonratchathani Cancer Centeren_US
dc.contributor.authorKanittha Promsumlee; Radiation Oncology Outpatient Department, Ubonratchathani Cancer Centeren_US
dc.contributor.authorMutita Sappsarn; Radiation Oncology Outpatient Department, Ubonratchathani Cancer Centeren_US
dc.date.accessioned2011-02-21T08:12:34Z
dc.date.available2011-02-21T08:12:34Z
dc.date.created2010-04-18en_US
dc.date.issued2010-04-18en_US
dc.description.abstractThe addition of radiation after mastectomy or breast conservative surgery in high risk breast cancer women can reduces the risk of locoregional recurrence. Weekly CBC is a routine monitor during the period of radiation. But the CBC abnormalities or bone marrow suppression is not much observed in our clinical practice.The purpose of this retrospective study was to evaluate the necessary of this routine practice. We had collected the CBC abnormalities in 122 stage I-III breast cancer patients who received postoperative radiation with or without preceding adjuvant chemotherapy in 2008.The finding showed that 27 % ,12.2 % and 2.4 % of patients had Hb \< 10 g% , ANC \< 1,500/mm3 and PLT \< 100,000 /mm3 in any weeks during radiation period. The mean duration between adjuvant chemotherapy and starting date of radiation were 4 weeks and 4.8 weeks in the patients who had abnormal CBC and no abnormal CBC respectively. Most of these abnornormalities occurred in the first 3 weeks of radiation.In our conclusion, routine CBC entired radiation period may not be necessary. CBC monitor in the first few weeks and clinical evaluation may be suffi cient.en_US
dc.identifier.citationJournal of Thai Society of Therapeutic Radiology and Oncology - วารสารมะเร็งวิวัฒน์; Vol. 16 No. 1 January – June 2010; 51 - 54en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/131240
dc.language.isoen_USen_US
dc.publisherJournal of Thai Society of Therapeutic Radiology and Oncology - วารสารมะเร็งวิวัฒน์en_US
dc.rightsThai Society of Therapeutic Radiology and Oncology, Bangkok, Thailanden_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/JTSTRO/issue/archiveen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/JTSTRO/article/view/3447en_US
dc.titleMyelosuppression in breast cancer patients receiving postoperative radiationen_US
dc.typeOriginal Articleen_US
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