Association of genital mycoplasmas including Mycoplasma genitalium in HIV infected men with nongonococcal urethritis attending STD & HIV clinics.

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dc.contributor.authorManhas, Ashwini
dc.contributor.authorSethi, Sunil
dc.contributor.authorSharma, Meera
dc.contributor.authorWanchu, Ajay
dc.contributor.authorKanwar, A J
dc.contributor.authorKaur, Karamjit
dc.contributor.authorMehta, S D
dc.date.accessioned2011-12-12T07:36:49Z
dc.date.available2011-12-12T07:36:49Z
dc.date.issued2009-03
dc.description.abstractBackground & objectives: Acute nongonococcal urethritis (NGU) is one of the commonest sexually transmitted infections affecting men. The role of genital mycoplasmas including Mycoplasma genitalium in HIV infected men with NGU is still not known. The aim of this study was to determine the isolation pattern/detection of genital mycoplasma including M. genitalium in HIV infected men with NGU and to compare it with non HIV infected individuals. Methods: One hundred male patients with NGU (70 HIV positive, 30 HIV negative) were included in the study. Urethral swabs and urine samples obtained from patients were subjected to semi-quantitative culture for Mycoplasma hominis and Ureaplasama urealyticum, whereas M. genitalium was detected by PCR from urine. The primers MgPa1 and MgPa3 were selected to identify 289 bp product specific for M. genitalium. Chalmydia trachomatis antigen detection was carried out by ELISA. Results: M. genitalium and M. hominis were detected/isolated in 6 per cent of the cases. M. genitalium was more common amongst HIV positive cases (7.1%) as compared to HIV negative cases (3.3%) but difference was not statistically significant. Co-infection of C. trachomatis and U. urealyticum was found in two HIV positive cases whereas, C. trachomatis and M. hominis were found to be coinfecting only one HIV positive individual. M. genitalium was found to be infecting the patients as the sole pathogen. Interpretation & conclusions: Patients with NGU had almost equal risk of being infected with M. genitalium, U. urealyticum or M. hominis irrespective of their HIV status. M.genitalium constitutes one of the important causes of NGU besides other genital mycoplasmas.en_US
dc.identifier.citationManhas Ashwini, Sethi Sunil, Sharma Meera, Wanchu Ajay, Kanwar A J, Kaur Karamjit, Mehta S D. Association of genital mycoplasmas including Mycoplasma genitalium in HIV infected men with nongonococcal urethritis attending STD & HIV clinics. Indian Journal of Medical Research. 2009 Mar; 129(3): 305-310.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/135789
dc.language.isoenen_US
dc.source.urihttps://icmr.nic.in/ijmr/2009/march/0314.pdfen_US
dc.subjectGenital mycoplasmasen_US
dc.subjectHIVen_US
dc.subjectMycoplasma genitaliumen_US
dc.subjectnongonococcal urethritisen_US
dc.subject.meshAdult
dc.subject.meshAmbulatory Care Facilities --statistics & numerical data
dc.subject.meshChlamydia Infections --epidemiology
dc.subject.meshChlamydia trachomatis
dc.subject.meshHIV Infections --epidemiology
dc.subject.meshHumans
dc.subject.meshIncidence
dc.subject.meshIndia --epidemiology
dc.subject.meshMale
dc.subject.meshMycoplasma Infections --epidemiology
dc.subject.meshMycoplasma genitalium --genetics
dc.subject.meshMycoplasma genitalium --isolation & purification
dc.subject.meshRisk Factors
dc.subject.meshUreaplasma Infections --epidemiology
dc.subject.meshUreaplasma urealyticum
dc.subject.meshUrethritis --epidemiology
dc.titleAssociation of genital mycoplasmas including Mycoplasma genitalium in HIV infected men with nongonococcal urethritis attending STD & HIV clinics.en_US
dc.typeArticleen_US
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