Role of Magnetic Resonance Enteroclysis in the Assessment of Pathologies of Small Bowel

dc.contributor.authorThirukoveluri, R.en_US
dc.date.accessioned2025-05-12T08:15:08Z
dc.date.available2025-05-12T08:15:08Z
dc.date.issued2024-08
dc.description.abstractbackground: Examination of the gastrointestinal (GI) tract for both anatomy and pathology is essential in diagnosing GI diseases. Traditional radiology has historically played a pivotal role, alongside endoscopy which remains primary despite limitations. However, non-invasive cross-sectional imaging modalities such as ultrasound (US), computed tomography (CT), positron-emission tomography (PET), and magnetic resonance imaging (MRI) have revolutionized GI tract assessment. These modalities offer enhanced resolution, 3D imaging, and contrast enhancement, with multimodal approaches such as PET-CT and PET-MRI improving sensitivity and specificity in tissue pathology studies. US, due to its affordability, non- invasiveness, and high diagnostic accuracy, has gained prominence in GI disease diagnosis, particularly with Doppler and contrast-enhanced US providing critical blood flow data. Magnetic resonance enteroclysis (MRE) has emerged as a standard imaging test for evaluating small-bowel (SB) pathologies, necessitating standardized practices in indications, interpretation, and methodology. MRE accurately assesses intraluminal, parietal, and extraluminal aspects of the SB, distinguishing between neoplastic and non-neoplastic diseases. This study aims to present the MRE technique, interpret imaging findings, and compare them with final diagnoses, emphasizing its role and advantages in diagnosing SB pathologies through rigorous methodological steps. Objective: This study evaluates the role of MRE in diagnosing SB pathologies, including inflammatory bowel diseases (IBD) and their extraluminal complications and extraintestinal manifestations. It focuses on assessing disease activity, treatment response, and distinguishing inflammatory from fibrotic strictures in conditions such as Crohn’s disease (CD) and ulcerative colitis (UC). Materials and Methods: A retrospective and prospective study conducted over 5 years starting from May 2019 to July 2024 (5 years) at the Department of Radiology, Sri Ramachandra Institute of Higher Education and Research, involved 34 patients with various SB pathologies undergoing MRE. Clinical and histopathological evaluations were compared with MRE findings. Statistical analysis determined the sensitivity and specificity of MRE as a diagnostic tool. Results: The study showed a slight male predominance among patients, with ages ranging from 1 to 80 years, most commonly affected between 21 and 40 years. Common symptoms included abdominal pain, vomiting, weight loss, and diarrhea. MRE identified bowel wall thickening, strictures, fat stranding, fistulas, lymph node enlargement, and ascites, with CD being the most prevalent diagnosis. Histopathological examination confirmed IBD in the majority as well as other pathologies such as tuberculosis and validating MRE diagnoses. Conclusion: MRE proves effective in diagnosing a wide range of GI pathologies, particularly inflammatory small-bowel disorders such as CD and UC. Its comprehensive imaging capabilities provide crucial insights for precise diagnosis and treatment planning, making it a preferred first-line imaging technique due to its non-invasiveness and absence of radiation exposure.en_US
dc.identifier.affiliations3rd Year Post Graduate Student, Department of Radiodiagnosis, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, Indiaen_US
dc.identifier.citationThirukoveluri R.. Role of Magnetic Resonance Enteroclysis in the Assessment of Pathologies of Small Bowel. International Journal of Scientific Study. 2024 Aug; 12(5): 38-55en_US
dc.identifier.issn2321-6379
dc.identifier.issn2321-595X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/246961
dc.languageenen_US
dc.publisherInternational Research Organization for Life & Health Sciencesen_US
dc.relation.issuenumber5en_US
dc.relation.volume12en_US
dc.source.urihttps://www.ijss-sn.com/uploads/2/0/1/5/20153321/ijss_aug_24_oa01_-_2024.pdfen_US
dc.subjectAcute myeloid leukaemiaen_US
dc.subjectChloromasen_US
dc.subjectExtramedullary ovarian granulocytic sarcoma/chloromaen_US
dc.subjectGranulocytic sarcomasen_US
dc.subjectHematopoietic and lymphoid tissuesen_US
dc.subjectLeukemia; Myelogenous; Chronic; BCR-ABL Positiveen_US
dc.subjectLeukemia; Myeloid; Acuteen_US
dc.subjectLeukemia; Promyelocytic; Acuteen_US
dc.subjectMyelodysplastic Syndromesen_US
dc.subjectMyeloid precursor cellsen_US
dc.subjectMyeloid sarcoma (granulocytic sarcoma or chloroma)en_US
dc.subjectOvarian granulocytic sarcomaen_US
dc.subjectPrimary ovarian granulocytic sarcomaen_US
dc.subjectSarcoma; Myeloiden_US
dc.titleRole of Magnetic Resonance Enteroclysis in the Assessment of Pathologies of Small Bowelen_US
dc.typeJournal Articleen_US
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