Pleomorphic Hyalinizing Angiectatic Tumor: Immunohistochemical Study with Review of Literature.
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Date
2015-01
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Abstract
Pleomorphic hyalinizing angiectatic tumor (PHAT) is relatively a new entity that was described first in 1996. Although it is often confused
with neurilemmoma and low grade malignant fibrous histiocytoma, it is considered to be a distinctive neoplasm because of certain unique
microscopic and immunohistochemical findings. It is a low grade, slowly growing tumor that recurs after surgical removal in about a third
of all cases. It is not known to metastasize. In this review, we have immunohistochemically analyzed a case of gluteal soft tissue tumor in
a 22-year-old woman using CD 34, CD 68, CD 99, S100 and desmin. Classical histological features and positivity for only CD 34 helped in
establishing the diagnosis as PHAT. We have reviewed the available literature.
Description
Keywords
CD 34/analysis, Extremities, Hyaline, Immunohistochemistry
Citation
Raghavan Vijayashree, Shivaprashanth K, Rao K Ramesh. Pleomorphic Hyalinizing Angiectatic Tumor: Immunohistochemical Study with Review of Literature. IJSS Case Reports & Reviews. 2015 Jan; 1(8): 46-49.