Comparative effects of atenolol versus nifedipine on serum lipids and other biochemical parameters in diabetic and non-diabetic hypertensive subjects.

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dc.contributor.authorSatia, M Cen_US
dc.contributor.authorShukla, M Len_US
dc.contributor.authorGoyal, R Ken_US
dc.date.accessioned1995-07-01en_US
dc.date.accessioned2009-06-01T07:27:36Z
dc.date.available1995-07-01en_US
dc.date.available2009-06-01T07:27:36Z
dc.date.issued1995-07-01en_US
dc.description.abstractA controlled clinical trial on 65 patients was performed to compare the effects of nifedipine and atenolol in diabetic and non-diabetic hypertensive patients. Patients were from 45 to 70 years in age. The diabetic hypertensive patients and non-diabetic essential hypertensive patients randomly received atenolol (50-100 mg per day) or nifedipine (10-20 mg per day) for 9 months. Both the drugs effectively controlled the blood pressure throughout the therapy. Atenolol treatment significantly increased triglyceride levels and decreased the HDL-cholesterol levels after 9 months in both groups. However, nifedipine therapy did not alter lipid levels to any significant extent. Both drugs did not alter blood glucose, serum creatinine and blood urea levels. It may be concluded from the present study that nifedipine is preferable to atenolol as it does not alter lipid profile to any significant extent in diabetic and non-diabetic hypertensive patients.en_US
dc.description.affiliationDepartment of Pharmacology, L. M. College of Pharmacy, Ahmedabad.en_US
dc.identifier.citationSatia MC, Shukla ML, Goyal RK. Comparative effects of atenolol versus nifedipine on serum lipids and other biochemical parameters in diabetic and non-diabetic hypertensive subjects. Indian Journal of Physiology and Pharmacology. 1995 Jul; 39(3): 237-41en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/108171
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAgeden_US
dc.subject.meshAntihypertensive Agents --adverse effectsen_US
dc.subject.meshAtenolol --adverse effectsen_US
dc.subject.meshBlood Glucose --metabolismen_US
dc.subject.meshBlood Pressure --drug effectsen_US
dc.subject.meshBlood Urea Nitrogenen_US
dc.subject.meshCreatinine --blooden_US
dc.subject.meshDiabetes Complicationsen_US
dc.subject.meshDiabetes Mellitus --blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHypertension --blooden_US
dc.subject.meshLife Styleen_US
dc.subject.meshLipids --blooden_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNifedipine --adverse effectsen_US
dc.titleComparative effects of atenolol versus nifedipine on serum lipids and other biochemical parameters in diabetic and non-diabetic hypertensive subjects.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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