Growth of the human lens in the Indian adult population: Preliminary observations.

Simple item page
dc.contributor.authorMohamed, Ashik
dc.contributor.authorSangwan, Virender S
dc.contributor.authorAugusteyn, Robert C
dc.date.accessioned2013-02-04T07:17:02Z
dc.date.available2013-02-04T07:17:02Z
dc.date.issued2012-11
dc.description.abstractContext: The eye lens grows throughout life by the addition of new cells inside the surrounding capsule. How this growth affects the properties of the lens is essential for understanding disorders such as cataract and presbyopia. Aims: To examine growth of the human lens in the Indian population and compare this with the growth in Western populations by measuring in vitro dimensions together with wet and dry weights. Settings and Design: The study was conducted at the research wing of a tertiary eye care center in South India and the study design was prospective. Materials and Methods: Lenses were removed from eye bank eyes and their dimensions measured with a digital caliper. They were then carefully blotted dry and weighed before being placed in 5% buffered formalin. After 1 week fixation, the lenses were dried at 80 °C until constant weight was achieved. The constant weight was noted as the dry weight of the lens. Statistical Analysis Used: Lens parameters were analyzed as a function of age using linear and logarithmic regression methods. Results: Data were obtained for 251 lenses, aged 16–93 years, within a median postmortem time of 22 h. Both wet and dry weights increased linearly at 1.24 and 0.44 mg/year, respectively, throughout adult life. The dimensions also increased continuously throughout this time. Conclusions: Over the age range examined, lens growth in the Indian population is very similar to that in Western populations.en_US
dc.identifier.citationMohamed Ashik, Sangwan Virender S, Augusteyn Robert C. Growth of the human lens in the Indian adult population: Preliminary observations. Indian Journal of Ophthalmology. 2012 Nov-Dec; 60(6): 511-515.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/144910
dc.language.isoenen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545126/en_US
dc.subjectGrowthen_US
dc.subjecthuman adulten_US
dc.subjectlens diameteren_US
dc.subjectlens dry weighten_US
dc.subjectlens thicknessen_US
dc.subjectlens wet weighten_US
dc.subject.lcshAdolescent
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshAged, 80 and over
dc.subject.meshAged
dc.subject.meshEye --growth & development
dc.subject.meshHumans
dc.subject.meshLens, Crystalline --anatomy & histology
dc.subject.meshLens, Crystalline --growth & development
dc.subject.meshIndia
dc.subject.meshTertiary Care Centers
dc.titleGrowth of the human lens in the Indian adult population: Preliminary observations.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijo2012v60n6p511.pdf
Size:
897.9 KB
Format:
Adobe Portable Document Format
Description:
Journal article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Indian Journal of Ophthalmology