High altitude marathon physiology changes

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dc.contributor.authorOak, Men_US
dc.contributor.authorOak, Aen_US
dc.contributor.authorOak, Ben_US
dc.date.accessioned2025-06-18T11:13:49Z
dc.date.available2025-06-18T11:13:49Z
dc.date.issued2025-06
dc.description.abstractHigh-altitude marathons present unique physiological challenges due to environmental factors such as reduced oxygen availability, decreased atmospheric pressure, and extreme temperature fluctuations. These conditions impose significant stress on the human body, requiring acute and chronic physiological adaptations to maintain performance. Acute responses include increased ventilation, elevated heart rate, and enhanced oxygen delivery mechanisms, while chronic adaptations involve hematological changes such as elevated erythropoiesis, cardiovascular remodeling, and skeletal muscle adaptations. Despite these adaptations, high-altitude conditions can substantially impact athletic performance, reducing aerobic capacity and increasing the risk of hypoxia-induced fatigue. Effective training and acclimatization strategies, such as altitude training camps and pre-acclimatization protocols, are critical for optimizing performance and minimizing the risks of high-altitude illnesses, including acute mountain sickness (AMS), high-altitude pulmonary edema (HAPE), and high-altitude cerebral edema (HACE). Furthermore, genetic predispositions, as observed in high-altitude native populations, may influence an athlete's ability to adapt to these environments. This review explores the interplay between environmental challenges, physiological adaptations, and athletic performance in high-altitude marathons. It highlights current strategies for preparation, potential medical risks, and future research opportunities in understanding the unique demands of high-altitude endurance events. Insights from this study aim to guide athletes, coaches, and medical professionals in optimizing training, performance, and safety during high-altitude marathons.en_US
dc.identifier.affiliationsOAK Hospital, Dombivli, Maharashtra, Indiaen_US
dc.identifier.affiliationsOAK Hospital, Dombivli, Maharashtra, Indiaen_US
dc.identifier.affiliationsOAK Hospital, Dombivli, Maharashtra, Indiaen_US
dc.identifier.citationOak M, Oak A, Oak B. High altitude marathon physiology changes. International Journal of Advances in Medicine. 2025 Jun; 12(3): 333-339en_US
dc.identifier.issn2349-3925
dc.identifier.issn2349-3933
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/248370
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber3en_US
dc.relation.volume12en_US
dc.source.urihttps://doi.org/10.18203/2349-3933.ijam20251086en_US
dc.subjectHigh altitude marathonen_US
dc.subjectHypoxiaen_US
dc.subjectVo2 Mxen_US
dc.subjectGeneticsen_US
dc.subjectTrainingen_US
dc.titleHigh altitude marathon physiology changesen_US
dc.typeJournal Articleen_US
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