Sleep in Epilepsy.
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Date
2013-07
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Abstract
The relationship between sleep and epilepsy is bidirectional. While certain types of
seizures occur almost exclusively during sleep, sleep deprivation can precipitate
seizures and can activate interictal epileptiform discharges (IEDs) in the
electroencephalogram (EEG). While non-rapid eye movement sleep is an activator of
IEDs and seizures, rapid eye movement sleep suppresses them. Nocturnal seizures
need to be distinguished from parasomnias. Epileptic seizures and IEDs result in
changes of sleep architecture, while antiepileptic drugs have variable effect on sleep
and wakefulness. Nearly one-third of patients with epilepsy complain day time
somnolence. In addition to nocturnal seizures and antiepileptic drugs (AEDs),
associated sleep disorders such as sleep apnoea and restless leg syndromes might be
responsible for daytime sleepiness in persons with epilepsy.
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Radhakrishnan Kurupth. Sleep in Epilepsy. Annals of the National Academy of Medical Sciences (India). 2013 Jul-Dec; 49(3&4): 161-168.