Crescentic Glomerulonephritis in a 65-year-old Male Patient with Lepromatous Leprosy: Case Report

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dc.contributor.authorBhutani, Pen_US
dc.contributor.authorKumar, Aen_US
dc.contributor.authorDhar, Men_US
dc.contributor.authorPathania, M.en_US
dc.date.accessioned2025-08-13T08:54:29Z
dc.date.available2025-08-13T08:54:29Z
dc.date.issued2025-06
dc.description.abstractLeprosy, a chronic infectious disease caused by Mycobacterium leprae, can involve multiple organ systems; however, renal manifestations are uncommon and often under-recognized, especially in the geriatric population. We report a rare case of a 65-year-old male with untreated multibacillary leprosy who presented with acute kidney injury and respiratory distress. Further evaluation uncovered an uncommon glomerular pathology (necrotising crescentic glomerulonephritis) necessitating both immunosuppressive therapy and multi-drug treatment for leprosy. This case highlights the diagnostic and therapeutic challenges in the geriatric population, where age-related changes, comorbidities, and atypical presentations can delay diagnosis. It underscores the importance of maintaining a high index of suspicion for leprosy and its systemic complications梚ncluding glomerulonephritis梕specially in older patients, where it is often overlooked. Early diagnosis through renal biopsy facilitated appropriate management in this patient. The case emphasizes the importance of integrated, multidisciplinary, and accessible healthcare approaches for older adults with leprosy, particularly those presenting with multi-organ involvement.en_US
dc.identifier.affiliationsMBBS, Senior Resident, Department of Geriatric Medicine, All India Institute of Medical Sciences Rishikesh, Uttarakhand, 249201, Indiaen_US
dc.identifier.affiliationsMBBS, Junior Resident, Department of Geriatric Medicine, All India Institute of Medical Sciences Rishikesh, Uttarakhand, 249201, Indiaen_US
dc.identifier.affiliationsMBBS, MD, Professor and Head, Department of Geriatric Medicine, All India Institute of Medical Sciences Rishikesh, Uttarakhand, 249201, Indiaen_US
dc.identifier.affiliationsMBBS, MD, Additional Professor, Department of Geriatric Medicine, All India Institute of Medical Sciences Rishikesh, Uttarakhand, 249201, Indiaen_US
dc.identifier.citationBhutani P, Kumar A, Dhar M, Pathania M.. Crescentic Glomerulonephritis in a 65-year-old Male Patient with Lepromatous Leprosy: Case Report. Indian Journal of Leprosy . 2025 Jun; 97(2): 195-200en_US
dc.identifier.issn0254-9395
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/250264
dc.languageenen_US
dc.publisherHind Kusht Nivaran Sangh (Indian Leprosy Association)en_US
dc.relation.issuenumber2en_US
dc.relation.volume97en_US
dc.source.urihttps://www.ijl.org.in/article-detail/97/546en_US
dc.subjectMultibacillary Leprosyen_US
dc.subjectOlder Adultsen_US
dc.subjectNecrotising Crescentic Glomerulonephritisen_US
dc.subjectAnti-GBM Diseaseen_US
dc.subjectLeprosy Related Nephropathyen_US
dc.subjectMulti-drug Therapyen_US
dc.titleCrescentic Glomerulonephritis in a 65-year-old Male Patient with Lepromatous Leprosy: Case Reporten_US
dc.typeJournal Articleen_US
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