Depigmentation therapies in vitiligo.

Simple item page
dc.contributor.authorGupta, Divya
dc.contributor.authorKumari, Rashmi
dc.contributor.authorThappa, Devinder Mohan
dc.date.accessioned2012-09-04T06:26:33Z
dc.date.available2012-09-04T06:26:33Z
dc.date.issued2012-01
dc.description.abstractDepigmentation therapy in vitiligo is an option in those with extensive vitiligo who have failed to respond to medical therapy and have obvious cosmetic disfigurement due to intervening patchy pigmented areas. Various aspects of this therapy such as the cost, treatment time, course, permanency of depigmentation, side effects, and the possibility of repigmentation should first be discussed with the patient. At present, there is no ideal depigmenting therapy available, but many agents in the market have been in use for many years. Monobenzyl ether of hydroquinone (MBEH) is the mainstay and Food and Drug Administration (FDA) approved in USA but takes many months to depigment and is associated with local side effects and risk of repigmentation. Other agents which are also used are 4-methoxy phenol and 88% phenol. Physical therapies for depigmentation include Q-switched ruby and alexandrite lasers and cryotherapy. Second-line agents which can be explored for depigmentation include imatinib mesylate, imiquimod, and diphencyprone. Many possible experimental agents are being explored like various phenol derivatives, melanoma vaccines, interferon gamma, busulfan, etc. A major lacuna still exists in this area and a lot more research is desirable to give satisfactory cosmesis to these patients with extensive vitiligo.en_US
dc.identifier.citationGupta Divya, Kumari Rashmi, Thappa Devinder Mohan. Depigmentation therapies in vitiligo. Indian Journal of Dermatology, Venereology and Leprology. 2012 Jan-Feb; 78(1): 49-58.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/140997
dc.language.isoenen_US
dc.source.urihttps://www.ijdvl.com/article.asp?issn=0378-6323;year=2012;volume=78;issue=1;spage=49;epage=58;aulast=Guptaen_US
dc.subject4-methoxy phenolen_US
dc.subjectdepigmentation therapyen_US
dc.subjectlasersen_US
dc.subjectmonobenzyl ether of hydroquinoneen_US
dc.subjectvitiligo universalisen_US
dc.titleDepigmentation therapies in vitiligo.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijdvl2012v78n1p49.pdf
Size:
705.71 KB
Format:
Adobe Portable Document Format
Description:
Journal article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Indian Journal of Dermatology, Venereology and Leprology