Conjunctival impression cytology in contact lens wearers.

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dc.contributor.authorSimon, Priyaen_US
dc.contributor.authorJaison, Saramma Gen_US
dc.contributor.authorChopra, Sudesh Ken_US
dc.contributor.authorJacob, Sunithaen_US
dc.date.accessioned2002-12-21en_US
dc.date.accessioned2009-05-29T09:12:08Z
dc.date.available2002-12-21en_US
dc.date.available2009-05-29T09:12:08Z
dc.date.issued2002-12-21en_US
dc.description.abstractPURPOSE: To evaluate the cytological changes in conjunctiva following regular contact lens wear and to determine the correlation, if any, between severity of cytological alteration and symptoms related to contact lens wear. METHODS: One hundred eyes (50 normal asymptomatic subjects) who served as a control group were studied by conjunctival impression cytology (CIC). These subjects were fitted with rigid gas permeable (RGP) or soft contact lenses and were followed up at the end of 3 and 6 months. At each follow-up visit the CIC was repeated. A filter paper with the impression specimen was stained with periodic acid schiff (PAS) and haematoxylin stain to study goblet cell loss. Papanicolaou stain was done to study squamous metaplasia. The cytological changes were graded using the system described by Natadisastra et al. RESULTS: Severity of cytological changes increased with the duration of contact lens wear (P = 0.00001). At the end of 6 months, 60% of symptomatic eyes wearing soft contact lens and RGP lens showed abnormal CIC changes. None of the asymptomatic RGP contact lens wearing eyes showed abnormal CIC changes whereas 33.4% of the asymptomatic soft contact lens wearing eyes showed abnormal CIC changes (P = 0.033). Epithelial changes occurred within 3-6 months of contact lens fitting. CONCLUSION: Severity of cytological changes increased with duration of lens wear (P = 0.00001). Prevalence and severity of cytological alteration is more in symptomatic contact lens wearers. Soft contact lens wearers although asymptomatic showed severe CIC changes.en_US
dc.description.affiliationDepartment of Ophthalmology, Christian Medical College and Hospital, Ludhiana 141 008, Punjab, India.en_US
dc.identifier.citationSimon P, Jaison SG, Chopra SK, Jacob S. Conjunctival impression cytology in contact lens wearers. Indian Journal of Ophthalmology. 2002 Dec; 50(4): 301-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/71332
dc.language.isoengen_US
dc.source.urihttps://www.ijo.inen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshChilden_US
dc.subject.meshConjunctiva --pathologyen_US
dc.subject.meshConjunctival Diseases --diagnosisen_US
dc.subject.meshContact Lenses --adverse effectsen_US
dc.subject.meshCytological Techniquesen_US
dc.subject.meshHumansen_US
dc.subject.meshTime Factorsen_US
dc.titleConjunctival impression cytology in contact lens wearers.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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