The challenge of antibiotic resistance: need to contemplate.

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dc.contributor.authorKapil, Artien_US
dc.date.accessioned2005-02-10en_US
dc.date.accessioned2009-05-27T07:13:07Z
dc.date.available2005-02-10en_US
dc.date.available2009-05-27T07:13:07Z
dc.date.issued2005-02-10en_US
dc.description67 references.en_US
dc.description.abstract"Survival of the fittest " holds good for men and animals as also for bacteria. A majority of bacteria in nature are nonpathogenic, a large number of them, live as commensals on our body leading a symbiotic existence. A limited population of bacteria which has became pathogenic was also sensitive to antibiotics to begin with. It is the man made antibiotic pressure, which has led to the emergence and spread of resistant genes amongst bacteria. Despite the availability of a large arsenal of antibiotics, the ability of bacteria to become resistant to antibacterial agents is amazing. This is more evident in the hospital settings where the antibiotic usage is maximum. The use of antibiotics is widespread in clinical medicine, agriculture, aquaculture, veterinary practice, poultry and even in household products. The major reason for this is the inappropriate use of antibiotics due to a lack of uniform policy and disregard to hospital infection control practices. The antibiotic cover provided by newer antibiotics has been an important factor responsible for the emergence of multi-drug resistant bacteria. Bacterial infections increase the morbidity and mortality, increase the cost of treatment, and prolong hospital stay adding to the economical burden on the nation. The problem is further compounded by the lack of education and " over the counter " availability of antibiotics in developing countries. Antibiotic resistance is now all pervasive with the developed world as much vulnerable to the problem. Despite advancement in medical technology for diagnosis and patient care, a person can still die of an infection caused by a multi-drug resistant bacteria. It is time to think, plan and formulate a strong antibiotic policy to address the burgeoning hospital infection.en_US
dc.description.affiliationDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi, India. akapil@micro@yahoo.comen_US
dc.identifier.citationKapil A. The challenge of antibiotic resistance: need to contemplate. Indian Journal of Medical Research. 2005 Feb; 121(2): 83-91en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/19793
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBacteria --drug effectsen_US
dc.subject.meshBacterial Infections --microbiologyen_US
dc.subject.meshDrug Resistanceen_US
dc.subject.meshHumansen_US
dc.subject.meshInfection Controlen_US
dc.titleThe challenge of antibiotic resistance: need to contemplate.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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