Progression and Outcomes of Chronic Kidney Disease Patients in District Hospitals

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dc.contributor.authorPongpitak Mikkataen_US
dc.contributor.authorDenpong Patanasethanonten_US
dc.contributor.authorSupon Limwattananonen_US
dc.date.accessioned2011-02-20T04:28:48Z
dc.date.available2011-02-20T04:28:48Z
dc.date.created2010-03-14en_US
dc.date.issued2010-03-14en_US
dc.description.abstractThe objective of this retrospective study was to determine the progression and outcomes of chronic kidney disease (CKD). Participants were patients who had serum creatinine (SCr) measurement in two district hospitals of Amnat Charoen province between 1 January 2003 and 31 December 2007. Based on definitions of the Kidney Disease Outcome Quality Initiative guideline, patients who had glomerular filtration rate (GFR) less than 60 ml/min/1.73 m² in two separate SCr measurements for at least 3 months were included. GFR was estimated using the abbreviated Modification of Diet in Renal Disease study equation. Descriptive statistics and Kaplan-Meier plots were used for analysis. At baseline, mean age was 61.5±11.3 years and 68.6% were female. At the end of a four-year follow up, 143 of 749 (19.1%) CKD stage 3 patients developed stage 4, 56 of 162 (34.6%) stage 4 patients developed stage 5, and 63 of 103 (61.2%) stage 5 patients died. Among the 103 stage 5 patients, 83 patients (80.6%) were hospitalized 4.7 times for 3.5 days, on average. For stage 4 or 5 patients, 2.3% of all prescriptions were unadjusted dosage regimens based on renal function. In conclusion, disease progression was still rapid in this study population leading to high rates of death and hospitalization. Further implementations on intervention aiming to slow the progression of patients with CKD in district hospitals should be conducted.en_US
dc.identifier.citationIsan Journal of Pharmaceutical Sciences - วารสารเภสัชศาสตร์อีสาน; Volume 5 No.3 September-December 2009; 202-210en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/130711
dc.language.isoen_USen_US
dc.publisherIsan Journal of Pharmaceutical Sciences - วารสารเภสัชศาสตร์อีสานen_US
dc.rightsIsan Journal of Pharmaceutical Sciences - วารสารเภสัชศาสตร์อีสานen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/IJPS/issue/archiveen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/IJPS/article/view/2227en_US
dc.titleProgression and Outcomes of Chronic Kidney Disease Patients in District Hospitalsen_US
dc.typeOriginal Articlesen_US
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