Immunogenicity of enhanced potency inactivated polio vaccine.

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dc.contributor.authorSingh, Jen_US
dc.contributor.authorRavi, R Nen_US
dc.contributor.authorDutta, A Ken_US
dc.contributor.authorKumari, Sen_US
dc.contributor.authorKhare, Sen_US
dc.date.accessioned1992-11-01en_US
dc.date.accessioned2009-05-27T05:37:16Z
dc.date.available1992-11-01en_US
dc.date.available2009-05-27T05:37:16Z
dc.date.issued1992-11-01en_US
dc.description.abstractFifty two children were immunized with two doses of enhanced potency inactivated polio vaccine in order to determine its efficacy. The vaccine was very efficacious with 92.3, 92.3 and 88.3% of the children seroconverting to the three poliovirus types, respectively. The vaccine was equally efficacious whether the two doses were given at 4-week or 8-week intervals or when immunization was started at 6-7 weeks of age or later. The presence of maternal antibodies did not interfere significantly with the seroresponse to two doses of IPV-E. The study recommends that two doses of IPV-E give satisfactory seroconversion rates. Immunization can be started as early as 6 weeks age and the two doses can be given at 4 weeks interval to complete primary immunization against poliomyelitis.en_US
dc.description.affiliationDepartment of Pediatrics, Lady Hardinge Medical College, New Delhi.en_US
dc.identifier.citationSingh J, Ravi RN, Dutta AK, Kumari S, Khare S. Immunogenicity of enhanced potency inactivated polio vaccine. Indian Pediatrics. 1992 Nov; 29(11): 1353-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/12097
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshAntibodies, Viral --blooden_US
dc.subject.meshDose-Response Relationship, Immunologicen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunization Scheduleen_US
dc.subject.meshInfanten_US
dc.subject.meshPoliomyelitis --prevention & controlen_US
dc.subject.meshPoliovirus --immunologyen_US
dc.subject.meshPoliovirus Vaccine, Inactivated --immunologyen_US
dc.titleImmunogenicity of enhanced potency inactivated polio vaccine.en_US
dc.typeJournal Articleen_US
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