Early results from indirect drug susceptibility test for tubercle bacilli.
dc.contributor.author | Mathew, S | en_US |
dc.contributor.author | Narayanan, A | en_US |
dc.contributor.author | Segaran, R | en_US |
dc.contributor.author | Paramasivan, C N | en_US |
dc.date.accessioned | 1999-05-22 | en_US |
dc.date.accessioned | 2009-05-27T08:09:09Z | |
dc.date.available | 1999-05-22 | en_US |
dc.date.available | 2009-05-27T08:09:09Z | |
dc.date.issued | 1999-05-22 | en_US |
dc.description.abstract | The indirect susceptibility test results on L-J medium for tubercle bacilli against streptomycin, isoniazid and rifampicin were read at the end of 2 wk and compared with the results at 4 wk. It was found that drug resistance could be correctly predicted in over 70 per cent of cultures including multi-drug resistant tuberculosis (MDR TB) strains at the end of 2 wk. The susceptibility to para-nitrobenzoic acid (PNB) read at 2 wk was able to distinguish non-tuberculous mycobacteria from Mycobacterium tuberculosis cultures. The early detection of resistance by this procedure requires only minimum inputs, and can benefit the majority of patients harbouring drug resistant tubercle bacilli. | en_US |
dc.description.affiliation | Tuberculosis Research Centre (ICMR), Chennai. | en_US |
dc.identifier.citation | Mathew S, Narayanan A, Segaran R, Paramasivan CN. Early results from indirect drug susceptibility test for tubercle bacilli. Indian Journal of Medical Research. 1999 May; 109(): 167-9 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/23422 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://icmr.nic.in/ijmr/ijmr.htm | en_US |
dc.subject.mesh | Antitubercular Agents --pharmacology | en_US |
dc.subject.mesh | Drug Resistance, Microbial | en_US |
dc.subject.mesh | Isoniazid --pharmacology | en_US |
dc.subject.mesh | Microbial Sensitivity Tests | en_US |
dc.subject.mesh | Mycobacterium tuberculosis --drug effects | en_US |
dc.subject.mesh | Nitrobenzoates --pharmacology | en_US |
dc.subject.mesh | Rifampin --pharmacology | en_US |
dc.subject.mesh | Streptomycin --pharmacology | en_US |
dc.subject.mesh | Tuberculosis, Multidrug-Resistant --microbiology | en_US |
dc.title | Early results from indirect drug susceptibility test for tubercle bacilli. | en_US |
dc.type | Journal Article | en_US |
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