Early results from indirect drug susceptibility test for tubercle bacilli.

dc.contributor.authorMathew, Sen_US
dc.contributor.authorNarayanan, Aen_US
dc.contributor.authorSegaran, Ren_US
dc.contributor.authorParamasivan, C Nen_US
dc.date.accessioned1999-05-22en_US
dc.date.accessioned2009-05-27T08:09:09Z
dc.date.available1999-05-22en_US
dc.date.available2009-05-27T08:09:09Z
dc.date.issued1999-05-22en_US
dc.description.abstractThe indirect susceptibility test results on L-J medium for tubercle bacilli against streptomycin, isoniazid and rifampicin were read at the end of 2 wk and compared with the results at 4 wk. It was found that drug resistance could be correctly predicted in over 70 per cent of cultures including multi-drug resistant tuberculosis (MDR TB) strains at the end of 2 wk. The susceptibility to para-nitrobenzoic acid (PNB) read at 2 wk was able to distinguish non-tuberculous mycobacteria from Mycobacterium tuberculosis cultures. The early detection of resistance by this procedure requires only minimum inputs, and can benefit the majority of patients harbouring drug resistant tubercle bacilli.en_US
dc.description.affiliationTuberculosis Research Centre (ICMR), Chennai.en_US
dc.identifier.citationMathew S, Narayanan A, Segaran R, Paramasivan CN. Early results from indirect drug susceptibility test for tubercle bacilli. Indian Journal of Medical Research. 1999 May; 109(): 167-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/23422
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAntitubercular Agents --pharmacologyen_US
dc.subject.meshDrug Resistance, Microbialen_US
dc.subject.meshIsoniazid --pharmacologyen_US
dc.subject.meshMicrobial Sensitivity Testsen_US
dc.subject.meshMycobacterium tuberculosis --drug effectsen_US
dc.subject.meshNitrobenzoates --pharmacologyen_US
dc.subject.meshRifampin --pharmacologyen_US
dc.subject.meshStreptomycin --pharmacologyen_US
dc.subject.meshTuberculosis, Multidrug-Resistant --microbiologyen_US
dc.titleEarly results from indirect drug susceptibility test for tubercle bacilli.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description: