Experience with amphotericin B in sodium stibogluconate--unresponsive cases of visceral Leishmaniasis in north Bihar.
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1994-09-01
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Abstract
One hundred cases of Indian Kala-azar unresponsive to sodium stibogluconate (SSG) were treated with amphotericin B. The drug was given in the dose schedule of 0.75 mg/kg body weight on alternate days intravenously dissolved in 5 percent dextrose solution. After 15 infusions given over a period of 30 days, all cases became clinically and parasitologically cured. Mild adverse reactions were noted during therapy. No relapse was observed at follow up after 12 months.
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Giri OP, Singh AN. Experience with amphotericin B in sodium stibogluconate--unresponsive cases of visceral Leishmaniasis in north Bihar. Journal of the Association of Physicians of India. 1994 Sep; 42(9): 690-1