Anticholesterol antibody: the way for reduction of hypercholesterolemia.

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dc.contributor.authorSarkar, Den_US
dc.contributor.authorLatif, S Aen_US
dc.contributor.authorAich, Jen_US
dc.contributor.authorUddin, S Nen_US
dc.date.accessioned2008-07-16en_US
dc.date.accessioned2009-05-27T03:52:50Z
dc.date.available2008-07-16en_US
dc.date.available2009-05-27T03:52:50Z
dc.date.issued2008-07-16en_US
dc.descriptionMymensingh Medical Journal. 10 references.en_US
dc.description.abstractAntibodies specific to cholesterol was first reported in 1925. It may develop in the body naturally and it is believed that this antibody has a protective role against harmful forms of cholesterol, such as LDL & VLDL. An immunoglobulin protein, anticholesterol may be found in both circulation as well as digestive tract. Many studies have been done on anticholesterol antibody. Our immune system may produce anticholesterol antibodies in response to elevated levels of cholesterol rich particles, such as LDL & VLDL. It can be induced in animals by conjugating or incorporating the cholesterol antigen into a variety of structures. Immunization markedly decreases the risk of developing atherosclerosis. In comparison to non-tumorous normal subject, the antibody is found to be significantly higher in non-small cell lung cancer (NSCLC). Elevated anti-cholesterol antibodies might be applicable for the serodiagnosis of NSCLC. Some studies showed that LDL immunization induces T-cell dependent antibody formation that protects atherosclerosis. Origo Biosciences scientists had identified a dietary antibody to cholesterol. This protein, when ingested, binds to cholesterol in the human digestive tract and blocks its absorption into the bloodstream. These studies may lead to us to realize the importance of anticholesterol and to find the way for reduction of hypercholesterolemia and thereby reduction of morbidity and mortality.en_US
dc.description.affiliationDepartment of Physiology, Mymensingh Medical College, Mymensingh, Bangladesh. mmcphysio logy@yahoo.comen_US
dc.identifier.citationSarkar D, Latif SA, Aich J, Uddin SN. Anticholesterol antibody: the way for reduction of hypercholesterolemia. Mymensingh Medical Journal. 2008 Jul; 17(2): 217-20en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/1149
dc.language.isoengen_US
dc.subject.meshAntibodies --blooden_US
dc.subject.meshAnticholesteremic Agents --therapeutic useen_US
dc.subject.meshCarcinoma, Non-Small-Cell Lung --diagnosisen_US
dc.subject.meshCholesterol --immunologyen_US
dc.subject.meshHumansen_US
dc.subject.meshHypercholesterolemia --immunologyen_US
dc.titleAnticholesterol antibody: the way for reduction of hypercholesterolemia.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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