Study of Normoalbuminuric Diabetic Nephropathy in Type 1 Diabetics

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dc.contributor.authorkumar, P K Senthilen_US
dc.contributor.authorBhaba, V Kannanen_US
dc.contributor.authorV, Ramasubramanianen_US
dc.contributor.authorHeber, Anandanen_US
dc.date.accessioned2020-10-16T08:38:26Z
dc.date.available2020-10-16T08:38:26Z
dc.date.issued2019-05
dc.description.abstractIntroduction: Diabetic kidney disease (DKD) is one of the primary causes of end-stage renal disease. Early diagnosis is veryimportant in preventing the development of DKD. Urinary albumin excretion rate and glomerular filtration rate (GFR) are widelyaccepted as criteria for the diagnosis and clinical grading of DKD, and microalbuminuria has been recommended as the firstclinical sign of DKD.Aim: The aim of the study was to study the existence of normoalbuminuric diabetic nephropathy in type 1 diabeticsMaterials and Methods: This prospective study was conducted in type 1 diabetic by documenting low c-peptide level. Fastinglipid profile was done in these patients. Serum electrolytes such as potassium, sodium, magnesium, and uric acid were measured.The characteristic profile of patients with duration of diabetes and low GFR was analyzed with respect to the duration of diabetes,serum magnesium level, hypertension, retinopathy, and renal biopsy features.Results: In 95 patients, of 17 patients with renal biopsy-proven normoalbuminuric diabetic nephropathy, 11 patients (65%) hadserum magnesium of <2 mg/dl, and only six patients had serum magnesium of >2 mg/dl. Among the 17 patients, five patients(29%) had hypertension and eight patients (47%) had diabetic retinopathy changes.Conclusion: There exists an entity – normoalbuminuric diabetic nephropathy in type 1 diabetic patients. The incidence ofnormoalbuminuric diabetic nephropathy increases with duration of diabetes.en_US
dc.identifier.affiliationsAssociate Professor, Department of Nephrology, Tirunelveli Medical College and Hospital, Tirunelveli, Tamil Nadu, Indiaen_US
dc.identifier.affiliationsAssistant Professor, Department of Nephrology, Tirunelveli Medical College and Hospital, Tirunelveli, Tamil Nadu, Indiaen_US
dc.identifier.affiliationsProfessor, Department of Nephrology, Tirunelveli Medical College and Hospital, Tirunelveli, Tamil Nadu, Indiaen_US
dc.identifier.affiliationsSenior Clinical Scientist, Department of Clinical Research, Dr. Agarwal's Healthcare Limited, Indiaen_US
dc.identifier.citationkumar P K Senthil, Bhaba V Kannan, V Ramasubramanian, Heber Anandan. ​Study of Normoalbuminuric Diabetic Nephropathy in Type 1 Diabetics. International Journal of Scientific Study. 2019 May; 7(1): 125-129en_US
dc.identifier.issn2321-595X
dc.identifier.issn2321-6379
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/209297
dc.languageenen_US
dc.publisherInternational Research Organization for Life & Health Sciences (IROLHS)en_US
dc.relation.issuenumber1en_US
dc.relation.volume7en_US
dc.source.urihttps://www.ijss-sn.com/uploads/2/0/1/5/20153321/26_ijss_apr_oa26_-_2019.pdfen_US
dc.subjectDiabetesen_US
dc.subjectNephropathyen_US
dc.subjectNormoalbuminuriaen_US
dc.titleStudy of Normoalbuminuric Diabetic Nephropathy in Type 1 Diabeticsen_US
dc.typeJournal Articleen_US
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