Primary CNS lymphoma: an audit of cases treated over a nine year period and review of the literature.

dc.contributor.authorLal, Pen_US
dc.contributor.authorHaldar, Sen_US
dc.contributor.authorDatta, N Ren_US
dc.contributor.authorAyyagari, Sen_US
dc.date.accessioned2009-05-28T07:14:37Z
dc.date.available2009-05-28T07:14:37Z
dc.date.issued2000-03-23en_US
dc.description23 references.en_US
dc.description.abstractPrimary CNS lymphoma is a rare tumor comprising around one percent of all brain tumors. This report is an audit of eight cases [5 males, 3 females, age range: 17-55 years] which were accrued over nine years. All patients underwent surgical decompression, followed by radical Radiotherapy [RT]. Five out of eight patients received adjuvant chemotherapy in the form of CHOP or PCV. Of the patients who relapsed two received CHOP as a salvage therapy, one received PCV therapy and lomustine with intrathecal methotrexate. At a median follow up of 16 months [range 1 to 39 months] the two year disease free survival and overall survival were 13 percent and 38 percent respectively, which is in accordance with the literature. High dose RT to whole skull with boost therapy is indicated for all the cases. However, the role of chemotherapy and the appropriate regime needs to be defined with certainty.en_US
dc.description.affiliationDepartment of Radiotherapy, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow-226 014, U.P., India.en_US
dc.identifier.citationLal P, Haldar S, Datta NR, Ayyagari S. Primary CNS lymphoma: an audit of cases treated over a nine year period and review of the literature. Indian Journal of Cancer. 2000 Mar; 37(1): 32-42en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/51076
dc.language.isoengen_US
dc.source.urihttps://www.indianjcancer.comen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshBrain Neoplasms --therapyen_US
dc.subject.meshDisease-Free Survivalen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLymphoma, Non-Hodgkin --therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSurvival Analysisen_US
dc.subject.meshTreatment Outcomeen_US
dc.titlePrimary CNS lymphoma: an audit of cases treated over a nine year period and review of the literature.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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